1 citations
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January 2013 in “MedChemComm” PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
123 citations
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May 2020 in “Drug Development Research” Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
66 citations
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January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
26 citations
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April 2007 in “Journal of pediatric gastroenterology and nutrition” A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.
October 2025 in “Records of Natural Products” Kaempferol promotes hair growth and could be a natural treatment for hair loss.
July 2025 in “Medical Science” Anabolic steroids and SARMs can cause serious liver damage.
25 citations
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June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
81 citations
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November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
44 citations
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September 2014 in “Cell Death & Differentiation” Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
28 citations
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November 2017 in “Molecular and cellular endocrinology” Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
56 citations
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February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
3 citations
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April 2024 in “Molecular Human Reproduction” Paxillin may help manage androgen-related disorders like PCOS by stabilizing androgen receptor proteins.
December 2024 in “Tissue and Cell” A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.
8 citations
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February 2009 in “Journal of Dermatological Science” Targeting androgen receptors with antiandrogen oligonucleotides could effectively treat hair loss.
57 citations
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February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
April 2025 in “Journal of Ethnopharmacology” Amygdalin in Persicae Semen may help treat hair loss by promoting hair growth and regulating key pathways.
January 2014 in “theses.fr (ABES)” Androgens regulate Sertoli cells and affect fertility through specific receptors and coregulators.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
195 citations
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May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
43 citations
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April 2011 in “AJP Endocrinology and Metabolism” Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
19 citations
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April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
1 citations
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August 2002 in “Zeitschrift für Hautkrankheiten” Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
1 citations
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June 2022 in “Frontiers in Neuroanatomy” Early hormones shape sex-specific differences in rat glands.
September 2025 in “Deleted Journal” Blocking androgen receptors boosts macrophages' ability to clear certain bacteria.
60 citations
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September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
23 citations
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August 2005 in “Expert opinion on pharmacotherapy” New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
18 citations
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May 2017 in “Experimental Dermatology” AMT may cause hair loss and changing dWAT activity could help treat it.
15 citations
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January 2009 in “International Journal of Andrology” Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
5 citations
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January 2024 in “Reproductive Medicine and Biology” Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.