72 citations
,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
66 citations
,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
5 citations
,
July 2019 in “Research Square (Research Square)” Yak hair growth is influenced by genes and hormones, helping them adapt to alpine environments.
41 citations
,
July 2002 in “Clinical and Experimental Dermatology” Effective hair loss assessment requires a mix of precise measurement methods.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
138 citations
,
May 2000 in “Maturitas” Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
119 citations
,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
24 citations
,
November 2016 in “Molecular Medicine Reports” Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.
3 citations
,
September 2014 in “Journal of obstetrics and gynaecology Canada” Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
50 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
March 2025 in “International Journal of Trichology” FAPD in children may not depend on androgens and should be treated with anti-inflammatory measures and minoxidil.
42 citations
,
August 2022 in “Diagnostics” Diagnose PCOS in teens using irregular periods and high androgen levels, not ultrasound.
13 citations
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December 2010 in “Pharmacology Biochemistry and Behavior” Inhibiting certain enzymes made female rats more sensitive to low-level pain.
November 2023 in “ACS Omega” New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
August 2023 in “Drug Design Development and Therapy” Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
57 citations
,
January 2022 in “Biomedicines” Curcumin may improve cancer radiotherapy by making cancer cells more sensitive to radiation and protecting normal cells.
1 citations
,
November 2023 in “Endocrine Connections” DHEA is the main sex steroid in cerebrospinal fluid, and testosterone in the fluid comes from the blood.
May 2023 in “Photobiomodulation, photomedicine, and laser surgery” The 675 nm laser treatment significantly increased hair density and reduced symptoms of androgenetic alopecia in both men and women, with no side effects.
1 citations
,
July 2022 in “Clinical dermatology review” Hair transplantation is an effective hair loss treatment with two main techniques, requires careful planning, and can improve beard and eyebrows appearance.
1 citations
,
October 2022 in “Springer eBooks” Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
January 2023 in “International journal of clinical medicine” Women with PCOS and hair loss have lower levels of the protein gelsolin in their blood.
August 2024 in “Dermatology and Therapy” Vorasidenib can cause unusual hair growth.
July 2023 in “JAAD International” Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
22 citations
,
July 1990 in “Acta Dermato Venereologica” High levels of testosterone and dihydrotestosterone inhibit hair cell growth, while high levels of estradiol promote it.
January 2025 in “Dermatologic Therapy” Targeting multiple pathways may improve treatments for androgenetic alopecia.
19 citations
,
February 2021 in “Journal of Clinical Investigation” More research is needed on the health effects of hormone therapy for transgender and nonbinary people.
January 2026 in “Clinics in Dermatology” Managing menopause symptoms like skin changes and hair thinning involves hormone therapy, procedures, and skincare, with emotional support being important.
November 2021 in “International Journal of Trichology” Low PON1 levels may indicate and predict the severity of hair loss.
December 2022 in “Clinical, Cosmetic and Investigational Dermatology” Androgenetic alopecia negatively affects quality of life, especially in younger, less educated, single, and rural individuals.
61 citations
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December 2001 in “Journal of Investigative Dermatology” Steroid sulfatase in hair follicles may be a target for treating hair loss.