research Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
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research Dihydrotestosterone Stimulates 5a-Reductase Activity in Pubic Skin Fibroblasts*
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research Combined oral contraceptives promote androgen receptor and oestrogen receptor alpha upregulation in the female prostate (Skene’s paraurethral glands) of adult gerbils (Meriones unguiculatus)
Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
research Lack of androgen receptor transcriptional activity in human keratinocytes
Human keratinocytes do not naturally respond to androgens.
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research An Investigation of Apoptosis in Androgenetic Alopecia
Apoptosis contributes to hair loss in androgenetic alopecia.
research Trichoscopy of Dark Scalp
Trichoscopy helps diagnose hair and scalp disorders in dark-skinned people by identifying unique patterns.
research Trichostasis spinulosa of the scalp mimicking Alopecia Areata black dots
A man's scalp condition was misidentified as hair loss dots but was actually a common follicular disorder.
research Skin and scalp under exposure to high-energy visible light: the current perspective
HEV light can harm or help skin and scalp, so safe exposure guidelines are needed.
research Hair and Scalp Dermatoscopy (Trichoscopy)
Trichoscopy is a useful tool for diagnosing and managing hair and scalp conditions, often better than traditional methods.
research High‐frequency ultrasonography of the scalp: A comparison between androgenetic alopecia and healthy volunteers
High-frequency ultrasound can effectively visualize and assess hair loss.
research Combined melanocytic nevus presenting with scalp alopecia associated with alopecia areata: Coincidence or causal?
A man's scalp hair loss was due to a combined melanocytic nevus and alopecia areata, suggesting a possible link between the two conditions.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Concept And Management of Androgenetic Alopecia (AGA) in Unani System of Medicine: A Review
Unani medicine offers a natural, effective approach to treating hair loss with minimal side effects, but needs more scientific validation.
research Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin.
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research Hair and scalp dermatoscopy
Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.
research HairMax LaserComb® Laser Phototherapy Device in the Treatment of Male Androgenetic Alopecia
HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Predictors of Scalp Hair Thinning in Women with Polycystic Ovary Syndrome
Scalp hair thinning in women with PCOS is linked to metabolic issues like abnormal glucose tolerance, high LDL, and skipped meals.
research Revitalizing Effect on the Scalp After Injection with a Mechanically Stabilized Hyaluronic Acid Complex in Subjects with Androgenetic Alopecia
The treatment improved hair thickness, shine, and reduced hair loss effectively.
research Correlation between sebum level and severity of male androgenetic alopecia
Higher sebum levels are linked to more severe male baldness.
research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
research The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Use of Minoxidil Sulfate versus Minoxidil Base in Androgenetic Alopecia Treatment: Friend or Foe?
Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
research Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells
Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
research Chronic telogen effluvium: Increased scalp hair shedding in middle-aged women
Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
research Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness
DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.
research Scalp Itch: A Systematic Review
The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.
research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq
WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
research Dirty Dots as a Normal Trichoscopic Finding in the Elderly Scalp
Dirty dots are a common scalp finding in elderly women and can be washed away with shampoo.