research Clinical use of 5α-reductase inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
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research Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment
New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
research Genetics of Polycystic Ovary Syndrome
PCOS has a strong genetic basis, but more research is needed to fully understand it.
research A Newborn With Hair Loss
The baby’s hair loss was due to a rare genetic condition, not treatable by usual methods.
research Hair Physiology (Hair Growth, Alopecia, Scalp Treatment, etc.)
The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
research Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies
Genetics can help tailor treatments for male pattern hair loss, improving outcomes like stabilization or modest regrowth.
research Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway
Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research Abstract 82
Fetal scalp cells have more regenerative genes than adult cells, and decellularized muscle matrix is better for muscle repair than commercial alternatives.
research Possible role of autophagy activation in stimulation of regeneration
The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research A Humanized Mouse Model of Hereditary 1,25-Dihydroxyvitamin D–Resistant Rickets Without Alopecia
Researchers created a mouse model of a type of rickets that does not cause hair loss.
research Ectodysplasin-A2 induces dickkopf 1 expression in human balding dermal papilla cells overexpressing the ectodysplasin A2 receptor
A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.
research Tissue engineering of human hair follicles using a biomimetic developmental approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers
Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
research The role of leptin in selected skin diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research Taking advantage from phenotype variability in a local animal genetic resource: identification of genomic regions associated with the hairless phenotype in Casertana pigs
Researchers found two genes that may explain why some Casertana pigs don't have hair.
research Recent updates on Wnt signaling modulators: a patent review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Marie Unna hereditary hypotrichosis caused by a novel mutation in the human hairless transcript
A new mutation in the HR gene causes hair loss in a specific family.
research The relationship among androgens, insulin resistanceand ghrelin polymorphisms in post-adolescent malepatients with severe acne vulgaris
Lower ghrelin levels and certain gene variations may increase acne risk.
research Epidermal expression of receptor for advanced glycation end products (RAGE) is related to inflammation and apoptosis in human skin
Skin RAGE levels are linked to inflammation and cell death.
research Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down‐regulation of 5α‐reductase type II
Plumbago zeylanica extract helps hair growth and reduces a hair loss-related enzyme.
research D2-40 Expression in Primary Scarring and Nonscarring Alopecia
Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.
research Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies
Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.
research 699 Effect of Prostaglandin D 2 on hair follicle growth and its impact on hair follicle stem/progenitor cells
Blocking Prostaglandin D₂ may help treat hair loss.
research 596 Application of an artificial intelligence (AI) photographic device to track platelet-rich plasma treatment outcomes in females with alopecia
An AI photographic device effectively tracked hair growth improvements in women treated for hair loss.
research 270 A novel small compound HPH-15 antagonizes TGF-β/Smad signaling and ameliorates experimental skin fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research Metabolic syndrome and alopecia: A case-control study
People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.
research A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.