March 2008 in “The Knowledge Bank (The Ohio State University)” SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.
April 2018 in “Gynäkologische Endokrinologie” Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
26 citations
,
January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
19 citations
,
April 2017 in “Synapse” Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.
8 citations
,
August 2011 in “Journal of Medicinal Food” D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
Antiandrogens and finasteride may help treat excess hair and hair loss in women.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
34 citations
,
July 1993 in “PubMed” 25 citations
,
March 2004 in “Regulatory Toxicology and Pharmacology” Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
19 citations
,
January 2016 in “Annals of Dermatology” Dutasteride is safe and effective for treating hair loss, but may decrease libido.
1 citations
,
November 2010 in “Anticancer Research” Finasteride and dutasteride both increase chromogranin A levels similarly.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
Testosterone undecanoate can reduce the negative effects of Finasteride on male reproductive health.
May 2024 in “Deleted Journal” Dutasteride effectively treats hair loss in men who don't respond to finasteride.
30 citations
,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
September 2017 in “ics.org” 13 citations
,
August 2016 in “Reproduction” High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
10 citations
,
March 1999 in “Comparative Haematology International” Androgens increase EPO production, finasteride doesn't significantly impact it.
1 citations
,
January 2000 in “PubMed” The treatment slightly increased hair growth and was safe for most women.
25 citations
,
November 2005 in “PubMed” Finasteride changes androgen receptor location in rat epididymis without altering tissue structure.
8 citations
,
March 2010 in “Gynecological Endocrinology” Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
December 1976 in “PubMed” Androgens affect skin conditions like acne and hirsutism, treatable with hormone therapy and other methods.
21 citations
,
January 2008 in “Journal of Pediatric Endocrinology and Metabolism” Anastrozole and cyproterone acetate treatment can help increase adult height in boys with testotoxicosis.
January 1978 in “Enlighten: Theses (The University of Glasgow)” Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.
96 citations
,
September 1975 in “The Journal of Clinical Endocrinology & Metabolism” Hormone levels change during puberty, leading to physical developments like pubic hair and voice changes.
12 citations
,
March 2018 in “Analytical chemistry” Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.
9 citations
,
November 1980 in “Geburtshilfe und Frauenheilkunde” Fenoterol treatment causes increased hair growth due to higher metabolism in hair follicles, not hormones.
155 citations
,
October 2002 in “The FASEB Journal” Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
4 citations
,
May 2019 in “Physiology & Behavior” Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
37 citations
,
December 2003 in “Reproductive Toxicology” The assay effectively detects hormonal activity of certain chemicals.