19 citations
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January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
18 citations
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December 2010 in “Journal of Trace Elements in Medicine and Biology” Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
18 citations
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” Hirsutism severity is linked to androgen levels, especially in women with a lower LH/FSH ratio.
17 citations
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April 2009 in “Andrologia” A boy's early puberty caused by a testicular tumor returned to normal after surgery.
17 citations
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February 2003 in “Australasian Journal of Dermatology” Hair loss in postmenopausal woman caused by ovarian issue.
14 citations
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January 1980 in “Dermatology” Cyproterone acetate temporarily reduces hair growth in women with idiopathic hirsutism but doesn't change hormone levels.
14 citations
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January 1980 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Both treatments reduced androgen levels and hair growth in women with hirsutism.
13 citations
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July 2008 in “Biomedical Chromatography” The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.
12 citations
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February 2023 in “Applied and Environmental Microbiology” Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.
12 citations
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February 2020 in “The Journal of Clinical Endocrinology & Metabolism” More body hair in young Australian women is linked to higher androstenedione levels.
11 citations
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January 2014 in “CellBio” Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.
11 citations
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March 1991 in “PubMed” Hormonal imbalances, including high prolactin and thyroid issues, contribute to hair growth problems in women.
10 citations
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May 2021 in “Psychoneuroendocrinology” Testosterone levels aren't important for depression in men, but some other hormones might affect certain symptoms.
10 citations
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November 2019 in “Neuroendocrinology” Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.
10 citations
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November 2018 in “Physiological Research” The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
10 citations
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January 2000 in “PubMed” Both finasteride and GnRH agonist treatments reduced hair growth in women with idiopathic hirsutism, but GnRH agonist was more effective.
9 citations
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November 2022 in “International Journal of Molecular Sciences” The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.
9 citations
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September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.
9 citations
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June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
9 citations
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December 1987 in “European journal of endocrinology” The treatment significantly reduced hair growth and male hormone levels in hirsute women.
8 citations
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March 2010 in “Gynecological Endocrinology” Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
7 citations
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January 2016 in “Experimental and Clinical Endocrinology & Diabetes” Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
7 citations
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September 1988 in “Baillière's clinical obstetrics and gynaecology” Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
7 citations
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December 1971 in “European Journal of Endocrinology” Human hair follicles can process steroid hormones like DHEA.
6 citations
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April 2019 in “Journal of Pediatric Endocrinology and Metabolism” Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.
6 citations
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June 2017 in “Reproductive Biomedicine Online” Chinese women with PCOS have higher androgen levels, which change with age and weight.
6 citations
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January 2009 In PCOS, high male hormones cause hair growth, acne, and hair loss, affecting periods.
5 citations
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April 2011 in “The Lancet” Untreated congenital adrenal hyperplasia can lead to complications like stroke and needs glucocorticoid treatment.
5 citations
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October 2010 in “General and Comparative Endocrinology” Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
5 citations
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July 1994 in “PubMed” Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.