June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Inflammation in hair follicles is a key risk factor for developing common baldness.
April 2023 in “Nigerian Journal of Clinical Practice” Hair loss in adults is linked to heart disease risk factors like unhealthy blood fats, lack of exercise, and alcohol use. It's also slightly more common in people with metabolic syndrome. As people age, hair loss gets worse. In men, severe hair loss is tied to high blood pressure and a larger waist. In women, it's tied to higher body weight. People with hair loss should be checked for unhealthy blood fats and advised to avoid alcohol and inactivity.
January 2010 in “Chinese Journal of Aesthetic Medicine” More severe hair loss and longer treatment improve results.
49 citations
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August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
27 citations
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February 2014 in “Experimental Dermatology” IGF-1 affects hair loss and could be a potential treatment.
7 citations
,
June 2015 in “European Journal of Plastic Surgery” PRGF treatment safely and effectively helps hair loss.
6 citations
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November 2020 in “Chinese Medical Journal” Combining minoxidil and fibroblast growth factor is more effective for treating male hair loss than using either alone.
August 2025 in “Bioactive Materials” Ac-GFFY-IGF peptide is a promising, safe, and effective treatment for hair loss, better than current options.
February 2025 in “BMC Public Health” Unhealthy diet and lifestyle choices may increase the risk of hair loss in women.
May 2024 in “Archives of dermatological research” LGFs slightly improve hair transplant results more than PRP.
May 2023 in “Journal of Cosmetic Dermatology” Using platelet-rich plasma, basic fibroblast growth factor, and minoxidil together significantly increases hair count and growth rate in people with hair loss.
April 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Combining PRP with LLLT is most effective for hair growth in androgenetic alopecia.
Bone Morphogenetic Proteins (BMPs) are important for hair growth, and their decrease due to hormones could lead to hair loss, but adding more BMPs could promote hair growth.
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
February 2009 in “Journal of The American Academy of Dermatology” People with early-onset hair loss have higher risk of heart issues, so early screening is important.
July 2023 in “Chinese Journal of Dermatology” Vascular endothelial growth factor might be involved in common hair loss.
April 2026 in “Dermatological Reviews” Ultrasound delivery of hair serum improves hair appearance and health more than microneedling.
July 2025 in “Journal of Investigative Dermatology” Reducing PEDF may help treat hair loss.
January 2022 in “Journal of Cosmetic Dermatology” Using basic fibroblast growth factor with minoxidil improves hair growth and patient satisfaction more than using minoxidil alone.
April 2018 in “Journal of Investigative Dermatology” Finasteride helps female-pattern hair loss.
100 citations
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August 2008 in “American Journal Of Pathology” VEGF-A is crucial for normal skin function and may be linked to psoriasis.
24 citations
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October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
October 2021 in “QJM: An International Journal of Medicine” Avoiding smoking, stress, obesity, and poor diet may help reduce hair loss in young Egyptian males.
January 2018 in “Przegla̧d dermatologiczny” Hair loss may increase heart disease risk.
15 citations
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May 2010 in “Actas Dermo-Sifiliográficas” Balding men have higher heart disease risk.
14 citations
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March 2016 in “Journal of Dermatology” Hair loss links to high blood pressure, high fat levels, and metabolic issues, suggesting early heart disease screening.
3 citations
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February 1990 in “Contact Dermatitis” Contact dermatitis may speed up hair loss in some cases.
2 citations
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July 2021 in “Journal of Cardiovascular Pharmacology” Lisinopril improves heart health more in men with normal hair than those with early hair loss.
September 2025 in “Journal of Medical Sciences and Health” Early-onset male hair loss may be linked to higher cardiovascular risk.
March 2025 in “Archives of Dermatological Research” Early-onset hair loss in Egyptian males is linked to genetics, hormones, and lifestyle factors like smoking and diet.