July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, but it improves after stopping the drug. The glycoprotein D vaccine works against genital herpes in some women, and the HPV-16 vaccine reduces HPV-16 infection and related diseases. More frequent light therapy clears psoriasis faster. A cream called imiquimod effectively treats a type of skin cancer. Iron supplements don't necessarily help with chronic hair loss in women.
13 citations
,
December 2024 in “Cellular and Molecular Life Sciences” Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
75 citations
,
June 2007 in “Journal of Biological Chemistry” MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
83 citations
,
October 2012 in “International Journal of Oncology” Wedelolactone selectively kills prostate cancer cells without harming normal cells.
November 2022 in “Journal of Investigative Dermatology” Apocynin may protect skin cells from aging and damage caused by UVB light.
7 citations
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March 2024 in “Non-coding RNA Research” DNA methylation of miR-365-1 causes hair follicle stem cell death by affecting DAP3.
January 2000 in “Cambio 16” Bcl-2 affects hair growth and pigmentation by controlling cell death.
123 citations
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December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
88 citations
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January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
70 citations
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February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
61 citations
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June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
57 citations
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June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
47 citations
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April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
34 citations
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April 2009 in “Expert Opinion on Pharmacotherapy” Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
25 citations
,
May 2014 in “Facial Plastic Surgery” PRFM may help treat hair loss, especially in mild cases.
13 citations
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July 2012 in “Dermatologic Surgery” Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.
11 citations
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September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
9 citations
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July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
8 citations
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August 2021 in “Aging” Berberine may reduce prostate enlargement by blocking inflammation.
3 citations
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April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
2 citations
,
January 2012 in “Hair therapy & transplantation” DDAIP-HCl significantly increases minoxidil absorption into the skin.
1 citations
,
January 2019 in “Elsevier eBooks” Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
June 2023 in “SDÜ Tıp Fakültesi Dergisi” Rutin may protect against stomach damage caused by sodium valproate.
February 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” Retinoic acid reduces cell damage from oxidative stress.
8 citations
,
January 2024 in “Medical Principles and Practice” IGFBP5 may be a potential target for Parkinson's treatment by reducing neuron death.
120 citations
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February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
7 citations
,
March 2005 in “Journal of dermatological science” Apoptosis helps shape hair growth and prepares the skin for hair to emerge.
1 citations
,
December 2023 in “Biomolecules” Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
271 citations
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May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.