research Circumscribed alopecia areata incognita
A rare form of alopecia causes hair thinning without bald spots and may be more common than thought, responding well to steroid treatment.
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930-960 / 1000+ results research The autoimmune basis of alopecia areata: A comprehensive review
Alopecia areata is caused by the immune system attacking hair follicles.
research Reversal of Canities in a Patient With Frontal Fibrosing Alopecia
A woman with hair loss condition experienced rare hair color return, suggesting it might help diagnose the condition.
research Treatment of Pseudofolliculitis Barbae
Combining proper shaving, topical treatments, and laser therapy effectively reduces Pseudofolliculitis Barbae.
research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection
Folliculotropic mycosis fungoides can affect the central nervous system in advanced stages.
research Th1/Th2 PB balance and CD200 expression of patients with active severe alopecia areata
Patients with severe active alopecia areata have lower CD200 expression and an imbalance in their immune system.
research Histopathologic prognostic factors for alopecia areata treated by intralesional corticosteroid
Certain scalp tissue features can predict how well alopecia areata responds to steroid injections.
research Supplementary Material for: TOFACITINIB IN OVERLAPPING AUTOIMMUNE AND AUTOINFLAMMATORY DISORDERS: A CASE REPORT OF A DUAL GRAHAM-LITTLE-PICCARDI-LASSEUR SYNDROME AND HIDRADENITIS SUPPURATIVA
Tofacitinib significantly improved symptoms in a patient with overlapping autoimmune disorders.
research Alopecia areata: A multifactorial autoimmune condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
research 700 Tyrosine kinase 2 inhibition rescues hair follicles from IL-12–mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse model
Inhibiting TYK2 can restore hair growth in alopecia areata.
research Les Rencontres d’Experts du Psoriasis : des recommandations pour la pratique quotidienne
Tofacitinib shows promise for treating severe alopecia areata with good safety and effectiveness.
research A 52-Week Real-Life Study of Baricitinib in Moderate to Severe Alopecia Areata: Clinical, Trichoscopic Assessment and Patient Reported Outcomes
Baricitinib significantly improved hair regrowth and quality of life in severe alopecia areata patients.
research Real‐life effectiveness and safety of baricitinib in adults with alopecia areata: A multicentre study
Baricitinib effectively reduces hair loss in alopecia areata and is well-tolerated.
research Multiple perifollicular fibromas: report of a case and analysis of the literature
Multiple perifollicular fibromas may actually be unrecognized cases of Birt-Hogg-Dubé syndrome.
research THE ROLE OF HAIR FOLLICLE COUNTS AND RATIOS IN THE HISTOPATHOLOGICAL ASSESSMENT OF ANDROGENIC ALOPECIA, ALOPECIA AREATA AND TELOGEN EFFLUVIUM: DOES COUNTING ‘COUNT’?
Hair follicle counts and ratios are helpful in diagnosing hair loss types, but should be used with other specific features for accurate diagnosis.
research Pseudofolliculitis barbae; current treatment options
The document concludes that stopping shaving or removing affected hair can alleviate Pseudofolliculitis barbae (PFB).
research Follicular cysts and hyperkeratoses in early mycosis fungoides
Acitretin effectively improved the woman's skin condition.
research Acute diffuse and total alopecia of the female scalp associated with borrelia-infection
A woman's total hair loss was linked to a Borrelia infection and was reversed with appropriate treatment.
research The challenging role of antiandrogens in the management of polycystic ovary syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research May AMH levels distinguish LOCAH from PCOS among hirsute women?
AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.
research Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata
Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
research Hair Follicle Biology and Signaling in Female Pattern Hair Loss: A Neuroendocrine Biomarker Perspective Integrated With Artificial Intelligence–Driven Precision Diagnostics
Female pattern hair loss can signal hormone issues and should be part of health checks for personalized treatment.
research Clinicotrichoscopic Patterns of Alopecia and the Prevalence of Thyroid Dysfunction in a Dermatology Outpatient Setting: A Cross‐Sectional Study
This cross-sectional study examined 100 patients with alopecia in a dermatology outpatient setting, focusing on the prevalence of thyroid dysfunction. The study found that alopecia was more common in younger individuals, with a mean age of 34.42 years, and a female predominance. Noncicatricial alopecia, particularly alopecia areata (37.03%), was more prevalent than cicatricial alopecia, with lichen planopilaris being the most common type (47.3%). Trichoscopic findings frequently included yellow dots and miniaturized hairs. Thyroid dysfunction was observed in 33.3% of noncicatricial and 42.1% of cicatricial alopecia patients, with subclinical hypothyroidism being the most common thyroid abnormality.
research Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center
Most patients with frontal fibrosing alopecia had facial bumps, with Hispanic/Latino and premenopausal women being more affected, suggesting a more severe condition.
research CD8 T cells require IFNg to induce disease in a murine model of Alopecia Areata 2310132
This study investigates the role of CD8 T cell-derived molecules in Alopecia Areata (AA) using a C3H/HeJ murine model. The research demonstrates that interferon gamma (IFNg) is a crucial effector molecule for CD8 T cells to induce AA, as IFNg-deficient CD8 T cells failed to transfer the disease. In contrast, perforin was found to be dispensable, as perforin-deficient CD8 T cells could still transfer the disease. Additionally, mice lacking the IFNg receptor (IFNgrKO) were unable to develop AA, highlighting the importance of IFNg sensing by the immune system in disease pathogenesis. These findings suggest that targeting IFNg pathways could be a potential therapeutic strategy for AA.
research Plasmacytoid dendritic cells as a key player in the initiation phase of alopecia areata-induced C3H/HeJ mouse
Plasmacytoid dendritic cells, which overproduce IFN-α, may play a crucial role in starting alopecia areata, an autoimmune disease causing hair loss.
research Excellent response to tofacitinib treatment in a patient with alopecia universalis
A patient with complete hair loss regrew all her hair using tofacitinib.
research 020 Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo
research Fibrosing Alopecia in a Pattern Distribution Localized on Alopecia Androgenetica Areas and Unaffected Scalp
A man with hair loss developed a condition causing scarring and inflammation in both bald and non-bald areas of his scalp.
research Hormonal Treatment for Skin Androgen-Related Disorders
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.