research Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
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research Endoplasmic reticulum in health and disease: the 12th International Calreticulin Workshop, Delphi, Greece
The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.
research Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing
Stem cell-derived vesicles show promise for healing diabetic wounds.
research Plant-Derived Exosomes: Nano-Inducers of Cross-Kingdom Regulations
Plant-derived exosomes can help deliver drugs and enable communication between different organisms.
research Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Alopecia and Periodontitis: Exploring the connecting dots
Dental care may help improve hair loss in alopecia patients.
research Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders
Exosomes could be a promising way to help repair skin and treat skin disorders.
research Clinical Applications of Extracellular Vesicles: Promises and Pitfalls
Extracellular vesicles show promise for medical use but face challenges in standardization and safety.
research Central nervous system demyelination associated with tofacitinib use in alopecia areata: A case report and literature review
Tofacitinib may cause nerve damage in the brain, so monitor for neurological symptoms.
research Immunohistochemical Pattern of CD34 Distribution in Different Types of Basal Cell Carcinoma and in Peritumoral Skin
CD34 is absent in most basal cell carcinoma cells but present in surrounding skin.
research Application of mesenchymal stem cells for anti-senescence and clinical challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research The Endocrine Function of the Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
research Mechanisms of autophagy and their implications in dermatological disorders
Targeting autophagy can help treat skin disorders like vitiligo and atopic dermatitis.
research Head and Neck 3D Bioprinting—A Review on Recent Advancements in Soft Tissue 3D Bioprinting and Medical Applications
3D bioprinting offers new ways to treat head and neck defects with bioinks that mimic natural tissues.
research 877 Small T antigen from a folliculotropic polyomavirus activates canonical Wnt/β-catenin signaling in vivo
A virus protein can activate a pathway that may lead to abnormal hair follicle development.
research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma
Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Evidence for murine cutaneous immune surveillance localized to hair follicle epithelium
Hair follicles in mice help detect and respond to germs.
research The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review
IVIG therapy significantly improved symptoms in a patient with APS-2 and SPS.
research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management
Restoring hair bulb immune privilege is crucial for managing alopecia areata.
research Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice
γδ T cells adapt uniquely to different tissues in mice.
research Sex-Specific Basal Metabolic Rate and NAFLD Risk: The Multi-Population Observational and Mendelian Randomization Study
Higher basal metabolic rate increases the risk of non-alcoholic fatty liver disease, especially in Chinese people, and may require tailored management.
research 033 IL-15 is an unexpected guardian of hair follicle immune privilege and promotes human hair growth ex vivo
IL-15 helps protect hair follicles from immune attacks and encourages hair growth.
research Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata
Early intervention with JAK inhibitors may prevent alopecia areata progression.
research Immune niches for hair follicle development and homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research Inflammatory loops in the epithelial–immune microenvironment of the skin and skin appendages in chronic inflammatory diseases
Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.