research Corticotropin releasing hormone and the skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
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930-960 / 1000+ resultsresearch Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice
Lack of vitamin D receptor increases skin tumor risk by boosting hedgehog signaling.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure
Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.
research Solid-State Fermentation for the Recovery of Phenolic Compounds from Agro-Wastes
Solid-state fermentation is an eco-friendly way to extract valuable compounds from agro-wastes for use in various industries.
research Activation and regulation of the granulation tissue derived cells with stemness-related properties
Granulation tissue-derived cells can aid wound healing and serve as an alternative source of stem cells for tissue repair.
research Presumptive Albendazole Toxicosis in 12 Alpacas
High doses of albendazole can be deadly for alpacas.
research Research progress on the natural products in the intervention of myocardial infarction
Natural products may be safer and effective alternatives for managing heart attacks.
research Selenium Compounds and Their Bioactivities: Molecular Mechanisms and Prospects for Functional Food and Therapeutic Applications
Selenium from plants is beneficial and safer for health.
research Lactic Acid Bacteria as Probiotics Improve Bioactive Compounds in Radix Angelica gigas (Danggui) via Solid-State Fermentation
Lactic acid bacteria fermentation boosts the health benefits of Radix Angelica gigas.
research Disease modifying osteoarthritis drug discovery using a temporal phenotypic reporter in 3D aggregates of primary human chondrocytes
Aromoline and DRD4 are potential targets for osteoarthritis treatment.
research Long-acting microneedle formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research Riboflavin-Sensitized Photo-Acceleration of Food-Grade Genipin Coloration: Kinetic Insights, Mechanistic Analysis, and Application in Rapid Hair Coloration
Riboflavin and blue light speed up genipin hair dye, making it fast, glossy, stable, and eco-friendly.
research Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems
TheDES improve drug delivery through the skin but need more safety checks.
research Anti-Inflammatory and Antifungal Activities of Wood Essential Oil from Juniperus morrisonicola Hayata
Juniperus morrisonicola wood essential oil has strong anti-inflammatory and antifungal properties.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses
Managing lipids may help treat hair loss.
research How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research Immunosuppressive treatment for proliferative lupus nephritis
Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.
research Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis
HDAC1 is crucial for skin development and preventing tumors.
research Monoterpenoid Loliolide Regulates Hair Follicle Inductivity of Human Dermal Papilla Cells by Activating the Akt/ ¥-Catenin Signaling Pathway
Loliolide can boost hair growth by activating specific cell pathways.
research Safety and quality of life of CDK4/6 inhibitors therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: a multicenter cross-sectional survey in China
CDK4/6 inhibitors affect safety and quality of life differently, requiring careful use.
research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Nanoparticles for Topical Application in the Treatment of Skin Dysfunctions—An Overview of Dermo-Cosmetic and Dermatological Products
Nanoparticles improve skin treatment but need more research on safety and effectiveness.
research Methotrexate for maintenance of remission in ulcerative colitis
Methotrexate is not proven to maintain remission in ulcerative colitis.
research Plasma Dermatology: Skin Therapy Using Cold Atmospheric Plasma
Cold atmospheric plasma is a promising and safe treatment for various skin conditions.
research Tissue engineering strategies combining molecular targets against inflammation and fibrosis, and umbilical cord blood stem cells to improve hampered muscle and skin regeneration following cleft repair
Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
research Design, Synthesis and Evaluation of N13-Substituted Evodiamine Derivatives against Human Cancer Cell Lines
N13-substituted evodiamine derivatives improved anticancer activity and solubility, showing promise for drug development.
research Invasion and increased expression of S100A4 and CYR61 in mesenchymal transformed breast cancer cells is downregulated by GnRH
GnRH treatment can reduce breast cancer cell invasion.
research Hormonal manipulation of benign prostatic hyperplasia
Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.