research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.
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research An Antifungal for Antidiuresis?
Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.
research Possible advantage of imiquimod and diphenylcyclopropenone combined treatment versus diphenylcyclopropenone alone: An observational study of nonresponder patients with alopecia areata
Combining imiquimod with diphenylcyclopropenone may improve treatment outcomes for alopecia areata patients who don't respond to diphenylcyclopropenone alone.
research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
New compounds may help treat prostate issues without affecting androgen receptors.
research Herd Report: Outbreak of Mixed Dermatophilosis and Pox Infection in Camels (Camelus dromedarius) in South Iraq
Camels in South Iraq were cured of skin infections with antibiotics and supplements.
research The efficacy of oral isotretinoin versus cyproterone compound in female patients with acne and the triad of cutaneous hyperandrogenism: A randomized clinical trial
Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.
research PTP1B Inhibitory and Anti-inflammatory Properties of Constituents from Eclipta prostrata L.
Compounds from Eclipta prostrata L. plant have diabetes and obesity-fighting properties and reduce inflammation.
research Use of Propolis for Topical Treatment of Dermatophytosis in Dog
Propolis was effective in treating ringworm and other skin conditions in dogs.
research EFFECT OF "AMINOPTERIN" ON EPITHELIAL TISSUES
Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.
research Alopecia areata and relapsing polychondritis or mosaic autoimmunity? The first experience of co-trimoxazole treatment
Co-trimoxazole successfully treated a girl with multiple autoimmune symptoms.
research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
research Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5α-reductase II
SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.
research Successful treatment of perifolliculitis capitis abscedens et suffodiens with combined isotretinoin and dapsone
Combining isotretinoin and dapsone effectively treated a challenging scalp condition.
research An Infectious Scalp Disorder
A 7-year-old girl's scalp infection was cured with oral medication and medicated shampoo.
research Tinea capitis favosa in Poland
Two patients with a rare scalp fungus in Poland were successfully treated with griseofulvin and ciclopirox.
research Treatment of idiopathic facial hirsutism with medroxyprogesterone acetate iontophoresis
Medroxyprogesterone acetate iontophoresis safely and effectively reduces facial hair growth in women.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Efficacy and tolerance of 2,3-diphenylcyclopropenone in propylene glycol versus 2,3-diphenylcyclopropenone in isopropanol – a novel formula designed for the treatment of alopecia areata
Both treatments helped hair regrowth in alopecia areata, with isopropanol being better tolerated.
research Management of pyoderma associated with demodicosis in a dog- A case report
The dog's skin disease was successfully treated with medication and supplements.
research A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice
The antibody 005-C04 blocks prolactin receptors, causing reversible infertility, impaired lactation, and hair regrowth in female mice.
research Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor
New hybrid compound found to effectively prevent hair loss.
research Inhibition of 5α-reductase alters pregnane metabolism in the late pregnant mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research Acute Alopecia Associated With Albendazole Toxicosis
Taking too much Albendazole can cause hair loss and other serious side effects.
research Acute Alopecia Associated With Albendazole Toxicosis
Taking too much Albendazole can cause hair loss and other serious side effects.
research Role of neurosteroids in the anticonvulsant activity of midazolam
Midazolam's seizure prevention is partly due to increased neurosteroid production.
research Abstract SS02-02: Chemoprevention: Poised for Success
Chemoprevention can significantly lower cancer risks and needs more research and collaboration.
research Progesterone and its Metabolites: Anticonvulsant and Behavioral Studies
Progesterone and its metabolites can prevent seizures without major side effects.
research Dermatophytosis Caused by Microsporum canis in a Free-Living Maned Wolf (Chrysocyon brachyurus).
A maned wolf was successfully treated for a fungal infection, highlighting the need to understand such diseases for conservation.
research 5-Alpha Reductase Inhibitors in Prostate Cancer: From Clinical Trials to Clinical Practice
5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.
research Recalcitrant alopecia areata responsive to leflunomide and anthralin—Potentially undiscovered JAK/STAT inhibitors?
Leflunomide and anthralin may effectively treat severe alopecia areata.