27 citations
,
February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.
January 2025 in “International Journal of Dermatology Research” Anagen grow may effectively treat hair loss by blocking testosterone and reducing enzyme activity.
218 citations
,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
104 citations
,
January 2005 in “Climacteric” Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
104 citations
,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
11 citations
,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
39 citations
,
March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
33 citations
,
January 2009 in “Contraception” Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
11 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
148 citations
,
April 2009 in “Molecular Pharmaceutics” Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
42 citations
,
February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
24 citations
,
January 2003 in “Journal of Investigative Dermatology” Blocking a specific receptor slows down hair loss in mice.
9 citations
,
March 1991 in “Endocrinology” Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
September 2012 in “The Egyptian Journal of Histology” Flutamide caused damage to male rat reproductive organs and may affect fertility.
Newer retinoid drugs are effective for skin conditions but have significant side effects.
3 citations
,
July 2020 in “Synthetic and Systems Biotechnology” Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.
1 citations
,
February 2025 in “South Asian Research Journal of Pharmaceutical Sciences” Eclipta alba flavonoids may help treat diabetes by effectively inhibiting Aldose reductase.
April 2025 in “Scientific Reports” Astragaloside A may help fight lung cancer by targeting specific proteins.
January 2024 in “Research Square (Research Square)” Traditional Chinese medicine may help treat ischemic stroke by targeting specific genes and pathways.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
555 citations
,
July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
425 citations
,
January 2021 in “SN Applied Sciences” Alginate is great for tissue engineering because it's safe, easy to use, and helps heal tissues.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
41 citations
,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
29 citations
,
July 2013 in “The Journal of Sexual Medicine” Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
25 citations
,
November 2013 in “PLoS ONE” Estrogen and androgen signals control synaptic changes in rat brains.
7 citations
,
January 2017 in “Biological & Pharmaceutical Bulletin” Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.
May 2021 in “Letters in Applied NanoBioScience” Pranlukast and mirabegron may work as new diabetes drugs.