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AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Decanoic acid may help treat PCOS by reducing androgen levels and improving glucose sensitivity.

Finasteride was successfully synthesized from Pregnadienolone acetate.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

IL-17 inhibitors are more effective than methotrexate in preventing psoriatic arthritis in psoriasis patients.

Rheumatology clinics should always provide preconception counseling for women on DMARDs.

Lambertianic acid helps prevent muscle wasting.

Altering SSAT affects fat metabolism and body fat in mice.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Steroid-producing capabilities in certain cancers may contribute to treatment resistance.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.

Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.

Aromatase inhibitors can cause various adverse reactions, so monitoring is crucial.

PAD enzymes play a key role in hair growth and structure.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

Depressed teens have different steroid levels in urine, which may help identify and treat them.

A reliable method was created to measure dutasteride and related molecules in capsules.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Leflunomide is more likely to help treat alopecia areata than cause it.

Finasteride reduces AML cell growth by inhibiting androgen receptors.

Correct diagnosis and treatment are crucial for effective management of lipid storage myopathies.

Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.