September 2025 in “JID Innovations” Squaric acid dibutylester promotes hair growth by activating immune cells, especially macrophages.
Mental health and hair loss are linked, and treating both can improve well-being.
March 2025 in “Clinical Reviews in Allergy & Immunology”
November 2024 in “The Journal of Cell Biology” Basement membrane changes are crucial for hair follicle development.
May 2024 in “Molecules/Molecules online/Molecules annual” Plant extracts can help prevent hair loss and promote hair growth.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
August 2023 in “International Journal of Molecular Sciences” The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
Thyroid problems can cause hair loss and change hair texture.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
January 2020 in “Egyptian Journal of Dermatology and Venereology” People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
April 2022 in “Journal of Investigative Dermatology” Androgenetic alopecia causes hair thinning due to increased androgen activity, treatable with minoxidil and finasteride.
58 citations
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February 2021 in “Toxins” Botulinum toxins effectively treat excessive sweating and may help with other skin conditions, but more research is needed.
5 citations
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July 2023 in “Frontiers in Veterinary Science” Combining PRP and MSCs improves skin healing and structure.
45 citations
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April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
24 citations
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January 2018 in “Development” Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
7 citations
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October 2022 in “Development” Overactive Wnt5a disrupts hair follicle orientation in mice.
7 citations
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January 2017 in “Stem Cells International” Neural organoids show promise for future CNS disease treatments.
February 2026 in “Journal of the American Academy of Dermatology” Ophiasis mainly affects females, lasts longer, and has lower regrowth rates, with a new classification system helping predict treatment response.
February 2021 in “Journal of Investigative Dermatology” Hair loss in male pattern baldness is linked to changes in specific genes and proteins that affect hair growth and scalp health.
4 citations
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January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
24 citations
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September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
22 citations
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July 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
3 citations
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July 2019 in “Journal of Cosmetic Dermatology” New shampoo with tyramine hydrochloride reduces hair loss by making a small muscle in the hair follicle contract.
2 citations
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September 2002 in “Dermatologic Surgery” Each group of hair follicles on the scalp shares one muscle that helps control hair movement.
1 citations
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February 2025 in “Scientific Reports” The method effectively analyzes skin tissue changes, especially in the arrector pili muscle and nerve fibers with hair follicles.
Curly hair may be caused by a muscle contraction, and muscle relaxants might help treat it.
November 2021 in “International journal of research - granthaalayah” The document suggests that human hair has electrical charges because of a gap in nerve cell coverage that affects electromagnetic radiation.
November 2017 in “Dermatologic Therapy” A new topical solution safely reduces hair shedding by 38% on average by tightening a muscle in the scalp.
15 citations
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February 2000 in “Journal of Cutaneous Pathology” The arrector pili muscle attaches to the extracellular matrix using α5β1 integrin and connects muscle cells using α1β1 integrin.