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α-MSH and cyclic AMP boost melanin production, while cyclic GMP and melatonin reduce it.

Environmental factors affect reproductive traits by altering the SRD5A1 gene.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Blocking EGFR can cause skin inflammation by disrupting IL-1 signaling.

Reduced matriptase activity causes skin and hair issues in both humans and mice.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.

MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.

HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.

AKR1C3 could be a treatment target for metabolic issues in PCOS.

Esrp1 is important for skin health by helping form and maintain the skin barrier.

AP-1 controls tumor cell type by affecting key signaling pathways.

Activating TRPMLs helps human cells important for hair growth and increases hair growth in mice.

A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Sphingosine 1-phosphate affects inflammation and gene expression in different aorta cells.

Cow milk sugars increase fat production and inflammation in skin oil cells.

LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.

Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.

Adipocytes in atopic dermatitis skin change and worsen inflammation and fibrosis.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.