20 citations
,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
August 2025 in “Journal of Medical and Life Science” Women with PCOS in Missan Province have higher weight, hormonal imbalances, and metabolic issues.
June 2016 in “The Egyptian Journal of Forensic Sciences and Applied Toxicology” Long-term exposure to benzene increases skin diseases, blood disorders, and liver problems.
9 citations
,
April 2023 in “World Journal of Clinical Cases” Test liver enzymes and triglycerides every 5-6 months, and cholesterol levels in the first two months for acne patients on isotretinoin.
September 2023 in “Translational medicine reports” Minoxidil ingestion can raise liver enzyme levels.
29 citations
,
July 2012 in “Fertility and Sterility” Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
June 2013 in “Ciencia e Investigación” Modified Aloe vera gel helped reduce liver damage and promote hair regrowth in mice.
2 citations
,
August 2020 in “Journal of Nutritional Science and Vitaminology” Yellow Chinese chive extract helps protect mouse livers from damage caused by acetaminophen by activating an antioxidant pathway.
August 2025 in “Nanomaterials” Tea polyphenol–zinc helps protect the liver and intestines from oxidative stress.
23 citations
,
August 1989 in “American Journal of Veterinary Research” High selenium diets in pigs cause health issues like weight loss, hair loss, and nerve damage.
2 citations
,
October 2024 in “Pharmaceutics” Smaller particle sizes of Tetrastigma hemsleyanum powders improve their effectiveness and liver health benefits.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
January 2021 in “Universal Journal of Pharmaceutical Research” Russelia equisetiformis extract protects against liver damage from paracetamol.
1 citations
,
January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” Zapoteca portoricensis extract may help protect against prostate issues and support liver and kidney health in rats.
2 citations
,
November 2017 in “Gynecological Endocrinology” The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.
1 citations
,
February 2014 in “Archiv Der Pharmazie” Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
April 2018 in “Journal of Investigative Dermatology” Mint water extract boosts protective enzymes in skin cells.
38 citations
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June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
29 citations
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December 2017 in “Molecular therapy” Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
116 citations
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May 1992 in “The American Journal of Medicine” Flutamide rarely causes liver toxicity in prostate cancer patients.
17 citations
,
January 2012 in “IOSR Journal of Environmental Science Toxicology and Food Technology” High doses of Tridax procumbens extract can be toxic, affecting liver and kidneys.
6 citations
,
December 2016 in “Journal of Dermatology” Dutasteride effectively and safely treats male hair loss for over a year.
1 citations
,
November 2019 in “International Journal of Dermatology” A 6-year-old girl with alopecia universalis regrew most of her hair after treatment with simvastatin/ezetimibe, minoxidil, and prednisolone.
December 2023 in “Journal of Science Innovations and Nature of Earth” Tribulus terrestris may protect the liver from drug damage.
15 citations
,
May 2006 in “Brain & development” Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
20 citations
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June 2015 in “Hormone Molecular Biology and Clinical Investigation” Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.
37 citations
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January 2010 in “Internal Medicine” A woman's liver was damaged by taking the herbal supplement Shou-Wu-Pian, but it got better after she stopped using it.
36 citations
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
14 citations
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October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.