September 2021 in “Eureka: Health Sciences” Androgenetic alopecia in women may be improved by targeting oxidative stress, inflammation, and fibrosis.
June 2025 in “Medical Science Journal for Advance Research” Higher levels of MIG and IP-10 may help diagnose and monitor Alopecia Areata.
January 2025 in “Frontiers in Immunology” IVIG therapy significantly improved symptoms in a patient with APS-2 and SPS.
10 citations
,
January 2023 in “Skin Appendage Disorders” Alopecia areata is an autoimmune hair loss condition linked to genetic factors.
3 citations
,
September 2025 in “Frontiers in Immunology” JAK inhibitors are effective for treating moderate-to-severe alopecia areata.
April 2017 in “Journal of Dermatological Science” B cells can both help and hinder the body's defense against melanoma.
2 citations
,
February 2018 in “InTech eBooks” TNF-alpha inhibitors can cause various immune-related skin issues.
Tofacitinib effectively regrows hair in alopecia universalis triggered by a virus.
November 2025 in “Frontiers in Immunology” Stem cell activity influences autoimmune disease outcomes by affecting immune responses and tissue regeneration.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
20 citations
,
February 2004 in “Clinical & Experimental Immunology” SADBE treatment led to complete hair regrowth in mice with alopecia areata by altering immune cell movement.
1 citations
,
June 2022 in “The Egyptian Journal of Hospital Medicine” Understanding the genetics of alopecia areata could lead to better treatments.
Some vaccines, like the hepatitis B vaccine, might be linked to the hair loss condition Alopecia Areata, but more research is needed.
March 2005 in “Journal of the American Academy of Dermatology” Higher levels of IL-1a and IL-1RA were found in severe alopecia areata cases.
60 citations
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January 1987 in “Dermatology” Alopecia areata may appear differently depending on the individual's type of hair loss and scalp condition.
July 2024 in “Journal of Investigative Dermatology” Modulating the BTNL2 pathway can prevent hair loss in mice.
52 citations
,
September 2014 in “Nature medicine” JAK inhibitors might help treat alopecia areata.
March 2011 in “Pigment Cell & Melanoma Research” The Agouti gene influences pigmentation and may have a developmental role in deer mice.
November 2025 in “Scholarly Commons (Embry–Riddle Aeronautical University)” Urban air pollution worsens hair loss in alopecia areata by increasing immune response.
11 citations
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July 2014 in “Gene” The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
1 citations
,
April 2017 in “Journal of Dermatological Science” Certain immune cells may cause hair loss by reacting to stressed hair follicles.
22 citations
,
June 2010 in “Experimental Dermatology” Lower MC2R expression may contribute to alopecia areata.
9 citations
,
April 2023 in “Experimental Dermatology” Allergen desensitization reduces hair loss severity in dust-mite allergic alopecia areata patients.
1 citations
,
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Fetal skin has unique immune cells different from adult skin.
4 citations
,
September 2012 in “Transplant international” Graft rejection in a hand transplant may trigger hair loss due to autoimmune responses.
IL-18 signaling helps mature Tregs move into the thymus.
19 citations
,
August 2008 in “Journal of The European Academy of Dermatology and Venereology” Bald areas have lower cell growth, more DNA damage, and increased cell death.
1 citations
,
August 2005 in “Springer eBooks” Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
9 citations
,
January 2015 in “Annals of dermatology/Annals of Dermatology” Alopecia areata in elderly people is usually mild and responds well to treatment.
1 citations
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April 2023 in “Portuguese Journal of Dermatology and Venereology” JAK inhibitors are effective treatments for alopecia areata.