research Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia
Potential therapeutic targets for scarring hair loss are identified.
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960-990 / 1000+ results research Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair Loss
Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Folate receptor β performs an immune checkpoint function in activated macrophages
Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
research Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?
Excessive sun protection might contribute to frontal fibrosing alopecia.
research Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution
Postmenopausal frontal fibrosing alopecia may be a unique condition linked to postmenopausal changes.
research Hair follicle stem cell-derived secretome protects astrocytes in an in vitro ischemia/reperfusion model
Hair follicle stem cell secretions may help protect brain cells and improve stroke recovery.
research Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration
Lymphatic vessels are essential for hair follicle regeneration and growth.
research Targeted Inactivation of Gh/Tissue Transglutaminase II
Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Epithelial elements in superficial angiomyxomas: mimicry of adnexal development, and mesenchymal‐to‐epithelial transition
Epithelial elements in superficial angiomyxomas are non-neoplastic growths mimicking embryogenesis.
research SnapshotDx Quiz: March 2016
JAK inhibitors may help treat alopecia areata by reversing hair loss.
research Extracellular Caspase-1 induces hair stem cell migration in wounded and inflamed skin conditions
Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
research Programming of induced pluripotent stem cells for hair follicle regeneration.
research Effect of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Nanofiber Matrices Cocultured With Hair Follicular Epithelial and Dermal Cells for Biological Wound Dressing
PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
research Immunohistochemical localization of tgf-β in alopecia areata
research Skin 3D Bioprinting. Applications in Cosmetology
3D bioprinting could improve skin repair and treat conditions like vitiligo and alopecia by precisely placing cells.
research Hair follicle stem cells: Walking the maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Cellular and extracellular involvement in the regeneration of the rat lower vibrissa follicle
Both cell and non-cell parts are important for rat whisker follicle regrowth.
research Eosinophils in fibrous tracts and near hair bulbs: A helpful diagnostic feature of alopecia areata
Eosinophils are not a reliable marker for diagnosing alopecia areata.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Injectable silk nanofiber hydrogels as stem cell carriers to accelerate wound healing
Silk nanofiber hydrogels help stem cells heal wounds faster and improve skin regeneration.
research Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors
Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
research Nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of tofacitinib for treating alopecia areata
Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
research Alterations of collagen type 1, skin fibroblasts, and macrophages in the scalp following the treatment of 1550‐nm erbium glass fractional laser for androgenetic alopecia
Laser treatment shows promise for hair growth, but needs further research.
research Mechanical engineering of hair follicle regeneration by in situ bioprinting
3D bioprinting can effectively regenerate hair follicles and skin tissue in wounds.
research Growth Factors, Cell-Cell and Cell-Matrix Interactions in Skin during Follicle Development and Growth
research FOXE1, A New Transcriptional Target of GLI2 Is Expressed in Human Epidermis and Basal Cell Carcinoma
research Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells
Recombinant Filaggrin-2 microneedles effectively promote hair growth and repair in hair loss.
research Platelet‐rich plasma for treatment resistant frontal fibrosing alopecia: A case report
Platelet-rich plasma (PRP) may help treat hair loss in patients with frontal fibrosing alopecia who don't respond to other treatments.