Recombinant Filaggrin-2 Microneedles Reverse Androgenetic Alopecia by Rescuing Mitochondrial Dysfunction in Dermal Papilla Cells
March 2026
in “
International Journal of Biological Macromolecules
”
Research cited in this study
34 / 34 results
research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment
Current treatments for androgenetic alopecia are complex and promising, but more research is needed.
research Photobiomodulation Mitigates DHT-Induced Apoptosis in Dermal Papilla Cells via Mitochondrial Rescue and Wnt/TGF-β/BMP Signaling Modulation
Photobiomodulation helps protect hair follicle cells from damage caused by DHT.
research Role of UVA-Driven Cellular Senescence via mTOR Activation in Dihydrotestosterone-Induced Hair Loss in Androgenetic Alopecia Mouse Model
UVA exposure worsens hair loss by activating a specific cell pathway.
research Force-Triggered Density Gradient Sedimentation and Cocktail Enzyme Digestion Treatment for Isolation of Single Dermal Papilla Cells from Follicular Unit Extraction Harvesting Human Hair Follicles
A new method improves the isolation of hair follicle cells for better hair growth research.
research Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting Circ_0135062/Mir-506-3p/Bax Axis
Botox can help prevent hair loss by blocking cell death in scalp cells.
research Molecular Mechanisms of Hair Follicle Development
Understanding hair follicle development helps create treatments for hair loss and improve hair health.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
research Activation of Mitochondrial Aldehyde Dehydrogenase 2 Promotes Hair Growth in Human Hair Follicles
Activating ALDH2 can boost hair growth.
research Androgenetic Alopecia: Therapy Update
There are many treatments for common hair loss, but more trials are needed to decide which are best.
research Advances in Microneedles Research Based on Promoting Hair Regrowth
Microneedles could be a better and easier way to regrow hair.
research Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways
Fish collagen peptides can significantly promote hair growth.
research Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells
Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
research Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts
Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
research Microneedling and Its Use in Hair Loss Disorders: A Systematic Review
Microneedling helps with hair loss, especially with 5% minoxidil, but more high-quality research is needed.
research The Inflammatory Component of Androgenetic Alopecia
Androgenetic alopecia, a genetic disorder affecting up to 50% of adults, is caused by an excessive response to androgens leading to hair follicle shrinkage. Treatments include FDA-approved drugs, other therapies like low-dose oral minoxidil, and hair transplantation.
research Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics
Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.
research Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment
Microneedles help treat hair loss by improving hair surroundings and promoting growth.
research The Potential Application of Ecklonia Cava Extract in Scalp Protection
Ecklonia cava extract may protect the scalp from pollution and improve its health.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage: An Experimental Animal Study
Finasteride may cause kidney damage.
research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.
research Scalp Condition Impacts Hair Growth And Retention Via Oxidative Stress
Healthy scalp reduces hair loss by managing oxidative stress.
research Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles
AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.
research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
research Psoriatic Alopecia
Psoriasis can cause temporary or permanent hair loss.
research Effects of Dihydrotestosterone on Rat Dermal Papilla Cells In Vitro
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
research Conditions Simulating Androgenetic Alopecia
Different hair loss types need accurate diagnosis for proper treatment.
research Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth
Growing human skin cells in a 3D environment can stimulate new hair growth.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment
Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration
S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
research Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses
Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
research Relative Influence of Ethanol and Propylene Glycol Cosolvents on Deposition of Minoxidil into the Skin
Ethanol over 50% helps minoxidil absorb better into skin.
research Pharmacokinetic Studies of Minoxidil
Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
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