77 citations
,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
75 citations
,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
75 citations
,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
38 citations
,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
30 citations
,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
25 citations
,
May 2013 in “Journal of mammary gland biology and neoplasia” Hedgehog signaling is crucial for mammary gland development over hair follicles.
19 citations
,
July 2018 in “Mechanisms of Ageing and Development” Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
19 citations
,
March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
19 citations
,
September 2004 in “Reviews in gynaecological practice” Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
11 citations
,
March 2008 in “Experimental Dermatology” A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
1 citations
,
January 2020 Ift20 is essential for hair follicle function and skin cell movement.
August 2025 in “Scientific Reports” C4BPA protein may link acne severity and insulin resistance.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
August 2022 in “Research Square (Research Square)” Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
2 citations
,
June 2021 in “Cosmoderma” Platelet-rich plasma (PRP) shows promise in skin and hair treatments but results vary with preparation methods.
2 citations
,
November 2023 in “Journal of Cosmetic Dermatology” Research on platelet-rich plasma in cosmetics has grown, but better studies are needed.
September 2021 in “VNU Journal of Science: Medical and Pharmaceutical Sciences” Platelet-rich plasma, which has growth factors, is used in many medical fields and can promote tissue repair, stimulate hair growth, and increase hair density.
August 2025 in “Journal of Polymer Science” AcD scaffolds improve tissue repair and regeneration by combining stem cells with a supportive matrix.
2 citations
,
December 2020 in “Developmental cell” Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.
4 citations
,
September 2021 in “Biomolecules” Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
222 citations
,
August 2014 in “Cell Metabolism” Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
28 citations
,
January 2023 in “Cell Transplantation” Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.
October 2024 in “Dermatologic Surgery” PRP and PRF show promise for hair growth but need more research for consistent and safe use.
426 citations
,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
PRP is promising for skin, hair, and wound treatments but needs standardized methods and more research.
May 2024 in “Journal of Cosmetic and Laser Therapy” Injectable platelet-rich fibrin improves hair growth and reduces hair loss in women.
14 citations
,
December 2022 in “Frontiers in Pharmacology” Combining negative pressure therapy with platelet-rich plasma speeds up healing and lowers death risk in diabetic foot ulcers.
2 citations
,
April 2025 in “Cells” Heat preconditioning does not improve nanofat's ability to form blood vessels.
January 2022 in “Springer eBooks” Combining PRP with lipofilling shows promise for tissue regeneration but needs more clinical trials to confirm benefits.