research Mesenchymal cell specific deletion of Tsc2 regulates hair follicle development and patterning
TSC2 is crucial for proper hair follicle development and patterning.
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research A pig model exploring the postnatal hair follicle cycle
Pigs are a good model for studying human hair growth and disorders.
research Synthesis and cross-linking in the structure and growth of hair keratins
The molecular details of hair growth are not well understood.
research 731 Generation of a laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlas
Scientists created a detailed map of gene activity in different parts of human hair follicles.
research Expression of type I hair keratins in follicular tumours
Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.
research Wnt target gene Ascl4 is dispensable for skin appendage development
The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
research Clinical characteristics, subtype classification, and prognostic factors of ophiasis: A retrospective study of 150 patients with therapeutic implications
Ophiasis mainly affects females, lasts longer, and has lower regrowth rates, with a new classification system helping predict treatment response.
research Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells
Scoparone may help stimulate hair growth by increasing stem cell-related proteins in skin cells.
research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
research Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos
Akt2 protein is essential for normal cell division in early mouse embryos.
research DNA determination of human hair bulbs in normal and androgenetic alopecia
Hair loss happens due to faster cell growth and fewer cells in affected follicles.
research Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain
Neurosteroids like allopregnanolone help control cell death and growth in the developing fetal brain.
research The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana tropicalis
Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
research PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair
PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
research EFFECTS OF STEROID HORMONES ON DEVELOPING MOUSE SKIN IN VITRO
Cortisol and corticosterone thin mouse skin and regress hair follicles, while testosterone promotes skin and hair development.
research Immunostaining study of cytokeratins in human hair follicle development
The study found that specific proteins are markers of hair follicle development in human fetuses.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis
research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin
Dermal papilla cells help skin stem cells grow into hair.
research Kinetics of blood cell differentiation during hematopoiesis revealed by quantitative long-term live imaging
Small changes in cell division and differentiation can activate blood progenitors.
research Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses
Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
research A single-cell transcriptome atlas during Cashmere goat hair follicle morphogenesis
The research mapped out the cell types and molecular processes involved in developing Cashmere goat hair follicles.
research Dynamic Transcriptome Profile Analysis of Mechanisms Related to Melanin Deposition in Chicken Muscle Development
Key genes influence melanin in chicken muscles, affecting their value.
research Analysis of Hair Follicles in Mutant Laboratory Mice
Understanding normal hair follicle development helps analyze abnormalities in mutant mice.
research Author response: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning
Understanding hair follicle interactions can help treat male pattern baldness.
research Connection between granulosa cell pyroptosis and oocyte endoplasmic reticulum stress in a mouse model of polycystic ovary syndrome
Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.
research Stem cell niches in mammals
Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
research Organotypic Cocultures as Models to Study Cell-Cell and Cell-Matrix Interactions of Human Hair Follicle Cells
Human dermal fibroblasts and hair papilla cells help outer root sheath cells grow and develop properly.
research Research Progress on the Molecular Mechanism of Poultry Feather Follicle Development
Key pathways like WNT, EGF, FGF, SHH, and BMP regulate poultry feather growth, with BMP inhibiting it.