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Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.

Propolis was effective in treating ringworm and other skin conditions in dogs.

Acyzol could help treat conditions caused by zinc deficiency.

Cucurbitacin helps mice grow hair by blocking a protein that stops hair growth.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Plant-derived amino acids can help develop new antimicrobial drugs.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Computer-aided methods can speed up COVID-19 drug discovery and help find new uses for existing drugs.

Herbal treatments may help manage seborrhea dermatitis effectively.

Solubility in skin changes with hydration, affecting chemical absorption.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Ketoconazole's structure and dynamics are linked, aiding antifungal drug development.

A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.

Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.

Ketoconazole shampoo can cause rare pink hair discoloration.

New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.

Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

Pharmacy-sold shampoos tend to have fewer allergens compared to those sold in other stores.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Certain drugs that block specific enzymes can help treat prostate diseases.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Galla chinensis solution effectively treats fungal skin infections in dogs.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Natural hydrolates may improve burn healing and fight antibiotic resistance.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Terbinafine and itraconazole are more effective against Microsporum canis than fluconazole and griseofulvin.