503 citations
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May 2009 in “Cell stem cell” Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.
14 citations
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March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.
The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.
20 citations
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November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
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January 2013 in “Journal of Investigative Dermatology” WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.
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June 2015 in “Journal of Investigative Dermatology” aPKCλ is crucial for keeping hair follicle stem cells inactive and maintaining normal hair growth.
16 citations
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November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
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June 2024 in “Genes” Key genes linked to wool quality in Spanish Merino sheep can improve fine wool production.
July 2025 in “Preprints.org” Specific miRNA profiles can help diagnose and treat alopecia areata.
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December 2024 in “Stem Cell Reports” Low fucosylation boosts stem cell growth in the eye.
164 citations
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February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
138 citations
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June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
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March 1994 in “PubMed” High ODC and low K1 and K10 may indicate early skin tumors in mice.
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
April 2019 in “Journal of Investigative Dermatology” Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
104 citations
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July 1994 in “The Journal of Cell Biology” Basonuclin helps keratinocytes multiply and prevents them from fully maturing.
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November 2022 in “Toxics” EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.
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March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
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November 1995 in “The EMBO Journal” Blocking EGFR in mice causes hair loss and skin changes.
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May 1999 in “Journal of Cutaneous Pathology” Apocrine type cutaneous mixed tumors often resemble hair follicles, sebaceous glands, and apocrine glands.
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January 2018 in “PubMed” Y-27632 helps hair follicle stem cells grow and keep their abilities.
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September 2019 in “PLoS ONE” K42 and K124 keratins are only found in horse hoof lamellae.
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January 2025 in “International Journal of Yoga” Yoga helps manage PCOS symptoms and improves overall health.
September 2025 in “American Journal of Dermatopathology” PRAME is often present in Paget disease and could help in diagnosis, but more research is needed.
April 2012 in “Cancer Research” Stat3 influences keratinocyte stem cell behavior, affecting differentiation and migration.
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September 2000 in “Journal of Biological Chemistry” GKLF/KLF4 and Sp1 control Keratin 19 gene activity, influencing cancer-related changes.
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October 2009 in “Veterinary Dermatology” Canine hair follicles contain stem-like cells with high growth potential.
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May 2011 in “Molecular Biology of the Cell” Integrin-linked kinase is crucial for normal skin healing.
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October 2023 in “Animals” Certain DNA regions in alpacas are linked to fiber diameter.
1 citations
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January 2003 in “The Pediatric Infectious Disease Journal” A 13-year-old boy had flu-like symptoms and low platelets after a camping trip, with a confirmed diagnosis later.