178 citations
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April 2011 in “Journal of Clinical Investigation” Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.
61 citations
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August 1993 in “PubMed” Basal cell epithelioma likely starts from the hair follicle's outer root sheath.
7 citations
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March 1993 in “International Journal of Oncology” Basal cell carcinoma shows keratin patterns similar to hair follicle structures.
351 citations
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February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
61 citations
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March 1966 in “Archives of Dermatology” Nevoid basal cell carcinomas start in the skin and hair follicles.
October 1998 in “RePub (Erasmus University, Rotterdam)” Basal cell carcinoma cases are rising globally.
9 citations
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January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
October 1998 in “Data Archiving and Networked Services (DANS)” Basal cell carcinoma cases are rising globally.
47 citations
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April 1978 in “Journal of Cutaneous Pathology” Basal cell epithelioma resembles fetal hair follicles, not adult or fetal skin.
3 citations
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March 1966 in “Archives of Dermatology” Nevoid basal cell carcinomas start in the skin's top layer and hair follicles.
1 citations
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April 2018 in “Journal of Investigative Dermatology” Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.
21 citations
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January 2018 in “Anticancer Research” NBCCS and BFHS might be the same syndrome, helping better identify and manage cases.
8 citations
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February 1994 in “Archives of Dermatology” Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.
1 citations
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January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
Basal cell carcinoma behaves like hair follicles and targeting specific pathways may help treat it.
37 citations
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May 1998 in “Journal of Dermatological Science” Basal cell carcinoma shows keratin patterns similar to undifferentiated hair follicle cells.
107 citations
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May 1999 in “Archives of Dermatological Research” Basal cell carcinoma may start from parts of tiny hair follicles.
January 2026 in “Medicina” CD34 is absent in most basal cell carcinoma cells but present in surrounding skin.
8 citations
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August 1987 in “The Journal of Dermatology” BKN-1 antibody targets specific keratin in basal cell epithelioma and normal skin basal cells.
128 citations
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February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
January 2016 in “eScholarship (California Digital Library)” HBCs in the olfactory epithelium can self-renew or differentiate into other cell types, with specific patterns during regeneration.
1 citations
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November 1983 in “The Lancet” Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.
1 citations
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November 2002 in “Journal of dermatology” The antibody created from BCC tissues reacts similarly to both BCC and hair follicles, suggesting BCC may come from hair follicle cells.
June 2025 in “Indian Journal of Dermatology” A rare skin condition was identified and planned for treatment in an elderly man.
Basaloid follicular hamartoma is a rare, benign skin growth often misdiagnosed.
146 citations
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February 2012 in “Journal of Clinical Investigation” Blocking Hedgehog signaling offers new treatment options for advanced basal cell carcinoma.
July 2019 in “Tumor Biology” Bone marrow-derived cells contribute to skin tumors, suggesting new treatment targets for non-melanoma skin cancers.
6 citations
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March 2018 in “The American journal of dermatopathology/American journal of dermatopathology” BerEP4 and CD34 staining can help tell apart tricholemmoma from basal cell carcinoma.
13 citations
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January 2010 in “PubMed”