research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors
LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
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research Inverted Follicular Keratosis in Young Adult: A Rare Entity in the Differential Diagnosis of Skin Tumors
Inverted Follicular Keratosis is rare but should be considered in scalp lesion diagnoses for all ages.
research Skin health of community-living older people: a scoping review
Older people at home often have skin issues, but there's little evidence on how to prevent or treat them effectively.
research Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis
Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
research Stem cell quiescence acts as a tumour suppressor in squamous tumours
Inactive hair follicle stem cells help prevent skin cancer.
research Expression of androgen receptors in skin appendage tumors: An immunohistochemical study
Androgen receptors are found in some skin tumors but not in hair follicle tumors.
research Spectrum of skin diseases in Yemen (Hajjah and adjacent region)
Most skin diseases in Hajjah, Yemen, were dermatitis, infections, and acne, influenced by local socioeconomic and environmental factors.
research Sox9 expression in canine epithelial skin tumors
Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice
CD34 is crucial for skin tumor development in mice.
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
research Genetic architecture of mouse skin inflammation and tumour susceptibility
Lgr5 and the vitamin D receptor are key in controlling skin inflammation and tumor risk in mice.
research Physiological and biological skin changes in pregnancy
Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
research Tumour regression predicts higher risk of sentinel node involvement in thin cutaneous melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways
Noggin promotes skin tumors by activating certain cell signaling pathways.
research Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research Dermoscopy of scalp tumours: a multi‐centre study conducted by the international dermoscopy society
The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.
research Metabolism and skin diseases
Skin health and diseases are closely linked to metabolic processes.
research Skin Diseases in Pregnancy
Pregnancy can cause various skin changes and diseases, requiring careful treatment to protect the baby.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research Differences in cell subsets between sun-exposed and unexposed skin: preliminary single-cell sequencing and biological analysis from a single case
Sun-exposed skin shows different cell activity and gene expression, suggesting targets to prevent skin aging and cancer.
research Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research The eye and the skin in endocrine metabolic diseases
Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
research Diseases of the skin. Treatment of scalp disorders.
The document concludes that scalp disorders can be treated with hair washing, specific shampoos, medications, and sometimes surgery or hair transplants, but hereditary baldness is untreatable.
research 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium
The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
research Tenascin expression in normal human adult skin and skin appendage tumours
Tenascin is present in normal skin and certain skin tumors but not in sebaceous glands or their tumors.
research Fibrotic enzymes modulate wound‐induced skin tumorigenesis
PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.
research Trichodiscoma. A Benign Tumor Related to Haarschibe (Hair Disk)
research New insights into the functions of Cox-2 in skin and esophageal malignancies
Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.