research Synthesis of a 4-azasteroid hormones compound
Finasteride was successfully synthesized from Pregnadienolone acetate.
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research A new catalyst for organic synthesis: mercuric triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research B/N-doped carbon nano-onions as nanocarriers for targeted breast cancer therapy
Boron/nitrogen-doped carbon nano-onions improve targeted breast cancer treatment by enhancing drug delivery and reducing side effects.
research Design, Synthesis and Evaluation of N13-Substituted Evodiamine Derivatives against Human Cancer Cell Lines
N13-substituted evodiamine derivatives improved anticancer activity and solubility, showing promise for drug development.
research Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Acitretin-Altered Squamous Cell Carcinoma
research Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity
Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
research On Photo-Stability of Oxybenzone
Estrogen receptors may not affect mouse hair growth as previously thought, and oxybenzone in sunscreen is stable in sunlight.
research On Pathways for Small Molecules Into and Out of Human Hair Fibers
Dye enters hair at the edges of cuticle cells and penetrates more from water than alcohol-based solutions.
research Abstract 1677: Epithelial hyperplasia induced by a selective B-Raf inhibitor, WYE-130600
WYE-130600 may cause skin thickening and irritation.
research Phytochemical composition, antibacterial and antioxidant activities of the ethanolic root extract of the endemic Onosma, northern Iran.
The ethanolic root extract of Onosma dichroantha has strong antioxidant and antibacterial properties.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Bisbenzylisoquinoline Alkaloids fromStephania cepharanthaand their Effects on Proliferation of Cultured Cells from the Murine Hair Apparatus
Certain compounds from Stephania cepharantha help hair cell growth.
research ChemInform Abstract: Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α‐Reductase Inhibitor.
A new compound may effectively inhibit the enzyme linked to BPH and hair loss.
research P-Phenylenediamine-Induced Angioedema-like Facies: A Case Report and Review of Pathomechanisms
Hair dye ingredient PPD can cause severe allergic reactions, including facial swelling.
research A discrete transition zone between cuticle and cortex layers of a human hair fibre: changes observed in the presence of breast cancer
Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
research Anthocyanin as Colorectal Anticancer: A Brief Review
Anthocyanins from fruits and vegetables may help prevent and treat colorectal cancer safely.
research Infiltrative Erythemas and Nodules on a Unilateral Cheek Following Inappropriate Use of a Topical Steroid
Improper steroid use can cause skin issues like rosacea, which may improve after stopping the steroid and using benzoyl peroxide.
research An unusual case of increased hair pigmentation in previously grey-white hair
A 73-year-old man's grey-white hair turned dark brown after eczema treatment.
research Detection of NUDT15 R139C variants and azathioprine utilization in patients with dermatologic conditions
research Carbonylation of hair proteins: A robust biomarker of molecular and structural oxidative damage in hair fibres
Protein carbonylation is a sensitive marker for oxidative damage in hair, especially from light exposure.
research Antibacterial potential and phytochemical analysis of two ethnomedicinally important plants
Echinops echinatus and Tridax procumbens have compounds that fight bacteria.
research One of the best treatments for alopecia areata remains unpublished
DNCB is highly effective for treating alopecia areata with minimal long-term side effects.
research Bioactivity guided isolation and characterization of the phytoconstituents from the Tridax procumbens
Tridax procumbens plant parts boost immune response in mice.
research ChemInform Abstract: Rα‐Reductase Inhibitors‐ — The Finasteride Story
research Imaging prostate cancer (PCa) with [99m Tc(CO)3 ]finasteride dithiocarbamate
A new compound was effective for imaging prostate cancer in rats.
research Anti-BPH lignans from Urtica triangularis subsp. pinnatifida (Hand.-Mazz.) C.J.Chen
Lignans from Urtica triangularis may help treat benign prostatic hyperplasia (BPH).
research Abstract 1718: Topical botanical extract for management of chemotherapy-induced alopecia.
A botanical extract was found to be a safe treatment that may prevent hair loss in chemotherapy patients.
research Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum japonicum : Glycosylation of Methyl Gallate with Ulosyl Bromides
Researchers created 10 new compounds similar to cercidin, which could lead to new antibiotics.
research ERYTHROMELANOSIS FOLLICULARIS FACIEI ET COLLI
Three Iranian men had reddish-brown facial pigmentation with no effective treatment.