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450-480 / 1000+ resultsresearch Nε-(carboxymethyl) lysine (CML) inhibits hair follicle formation by suppressing hair bulb condensation
research Determination of vinflunine in Beagle dog′s plasma by LC-MS and study of its pharmacokinetics
The method accurately measures vinflunine in dog plasma.
research Preparation of finasteride by selective dehydrogenation using IBX
The method produces finasteride with a 92% yield.
research GC determination of eleven kinds of residual solvents in Finasteride
The method accurately and reliably detects residual solvents in Finasteride.
research [The treatment of epilepsies with Convulsofin].
Convulsofin effectively treats primary epilepsy but has some side effects.
research The induction of cashmere shedding via cyclophosphamide injection
Cyclophosphamide effectively induces cashmere shedding in goats without affecting their overall health.
research Anti-androgenetic effect of diphlorethohydroxycarmalol on testosterone-induced hair loss by inhibiting 5α-reductase and promoting Wnt/β-catenin signaling pathway in human dermal papilla cells
Diphlorethohydroxycarmalol may help treat hair loss better than current medications.
research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia
LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.
research Neurosteroid Synthesis-Mediated Regulation of GABAAReceptors: Relevance to the Ovarian Cycle and Stress
Ovarian and stress hormones can change GABA A receptors through neurosteroids.
research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia
LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.
research Cedrol mitigates hepatic lipid accumulation and adipocyte hypertrophy induced by corticosteroids through the inhibition of glucocorticoid receptor activity
Cedrol may help reduce liver fat and fat cell growth caused by corticosteroids.
research Promising Protocol for In Vivo Experiments with Betulin
A new method improves betulin delivery and shows promise in cancer treatment.
research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)
The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
research Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice
research Testosterone and doping control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research The effects of acute finasteride treatment in dopamine transporter knockout mice and MK-801-treated mice
research Null Mutation of 5α-Reductase Type I Gene Alters Ethanol Consumption Patterns in a Sex-Dependent Manner
research Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids
The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
research PROCESS VALIDATION OF BETA-SITOSTEROL HAIR GEL FORMULATION AND EVALUATION OF 5 ALPHA REDUCTASE INHIBITION IN VITRO FOR THE TREATMENT OF ANDROGENETIC ALOPECIA
The β-sitosterol hair gel is effective and promising for treating hair loss.
research 10.51847/1z2Yt2O
SFE is a better extraction method, and the HPTLC method is effective for analyzing wedelolactone in E. alba.
research Comparison of comedolytic effect of benzoyl peroxide and adapalene in rhino mice
Benzoyl peroxide and adapalene gels work differently to reduce acne in mice.
research Effects of Solvent System and Storage Condition on Chemical Stability of 5(alpha)-Reductase Inhibitor Compounds in Tectona grandis L.f. Leaf Extracts
Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
research Synthesis of minoxidil conjugates and their evaluation as HL-60 differentiation agents
Some minoxidil combinations can help differentiate leukemia cells without harming other cells.
research In silico analysis of ethyl acetate Bruguiera gymnorhiza leaf extracts as an anti-inflammatory agent
Bruguiera gymnorhiza leaf extracts show potential for developing anti-inflammatory drugs.
research Acute and 30-day oral toxicity studies of a novel coccidiostat – ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research Increased anxiety‐like phenotype in female guinea pigs following reduced neurosteroid exposure in utero
Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.