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research 5α-Reductase inhibitor therapy: Should physicians be concerned with persistent diminished libido, erectile dysfunction and depression in a subset of patients?
Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
research Total prostate volume as risk factor for semen pathologies in ageing male
Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
research Female pattern hair loss, sebum excretion and the end-organ response to androgens
Hair loss in women not always linked to increased oil production; other factors may be involved.
research Management of polycystic ovary syndrome in adolescence
Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.
research Biology of Hair Growth and Influence of External Factors (Ecology, Stress, Nutrition
External factors like pollution, stress, and poor nutrition can negatively affect hair growth.
research An Investigation of Apoptosis in Androgenetic Alopecia
Apoptosis contributes to hair loss in androgenetic alopecia.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research Redox-Responsive Polymer Dot Nanozymes Coordinate Exosome-Mediated Cutaneous Regeneration via Laser-Modulated Microenvironment Remodeling
Polymer dot nanozymes and exosomes, with laser stimulation, speed up wound healing.
research Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research Approaches to lifestyle management in polycystic ovary syndrome
Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.
research Post-steroid panniculitis: a lost and forgotten entity?
Post-steroid panniculitis is now rare because doctors taper steroids more carefully.
research There is no clear association between low serum ferritin and chronic diffuse telogen hair loss
Low iron levels are not directly linked to chronic hair loss and iron supplements may not help.
research Interventional studies for polycystic ovarian syndrome in children and adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research The Osler Lecture 2012 'Pharmacology 2.0, medicines, drugs and human enhancement'
The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.
research PCOS in adolescents
PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
research Hormonal treatment of acne vulgaris: an update
Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
research Revisiting hyper- and hypo-androgenism by tandem mass spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
research Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research The use of cyproterone acetate/ethinyl estradiol in hyperandrogenic skin symptoms – a review
Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
research Drug-induced postinfantile giant cell hepatitis
Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.
research The use of testosterone after menopause
Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.
research Therapeutic targeting of ocular diseases with emphasis on PI3K/Akt, and OPRL pathways by Hedera helix L. saponins: a new approach for the treatment of Pseudomonas aeruginosa-induced bacterial keratitis
PEVIII is a promising treatment for Pseudomonas aeruginosa keratitis.
research Letter to the Editor on “COVID-19 Infection in Men on Testosterone Replacement Therapy”
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research The Impact of Lactobacillus-Rich Probiotic Nutrition on the Pharmacological Efficacy of Clotrimazole Delivered via Mucoadhesive Thermosensitive Hydrogels in Human Subjects with Recurrent Candidiasis
Combining probiotics, clotrimazole gel, and laser therapy improves treatment for recurrent yeast infections.
research Elevated serum chromogranin A levels are independently associated with metabolic and inflammatory disturbances in polycystic ovary syndrome
High chromogranin A levels are linked to obesity and inflammation in polycystic ovary syndrome.
research Liver function congruence with contraceptive medical profile in women at child-bearing ages
Long-term use of hormonal contraceptives may harm liver function.
research Hirsutism due to polycystic ovarian syndrome: An integrative review of pathophysiology and management
Combining modern and Unani treatments may offer better care for hirsutism in PCOS.
research Androgen Treatment in Women
Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
research Androgen Treatment in Women
Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.