research Long-Term Differential Changes in Mouse Intestinal Metabolomics after γ and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
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300-330 / 1000+ results research Application of the waiting time distribution in a nationwide screening of real‐world dermatology drug utilization for aberrant use patterns
Most dermatology drugs in Denmark are used correctly, with few unusual patterns.
research Evaluation of hair follicles as a surrogate tissue for pharmacodynamics response in xenograft tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
research Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Partial biotinidase deficiency: Clinical and biochemical features
Children with partial biotinidase deficiency are healthy at birth but may develop symptoms that improve with biotin therapy.
![Influence of FHIT on Benzo[a]pyrene-Induced Tumors and Alopecia in Mice: Chemoprevention by Budesonide and N-Acetylcysteine](/images/research/f8f56777-f891-4879-8c45-c87d6aa82563/small/35499.jpg)
research Influence of FHIT on benzo[ a ]pyrene-induced tumors and alopecia in mice: Chemoprevention by budesonide and N -acetylcysteine
Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.
research Consumption of a low-carbohydrate and high-fat diet (the ketogenic diet) exaggerates biotin deficiency in mice
The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
research Analytical method for the biomonitoring of bisphenols and parabens by liquid chromatography coupled to tandem mass spectrometry in human hair
A new method accurately detects bisphenols and parabens in human hair.
research What’s new in Birt–Hogg–Dubé syndrome?
New findings suggest the protein linked to Birt–Hogg–Dubé syndrome is important in cell signaling and could affect treatment understanding.
research Plucked human hair as a tissue in which to assess pharmacodynamic end points during drug development studies
Plucked human hair can be used to study drug effects on certain cell markers.
research Contents
Biologicals are increasingly used in medicine and cosmetics, especially for skin and hair treatments, but more research is needed.
research A Point to Consider in the Statistical Analysis of Scientific Studies
research ГНОТОБИОНТЫ – ЭКСПЕРИМЕНТАЛЬНАЯ МОДЕЛЬ
Controlled microflora in animals delays immune cell maturation and affects immunity.
research Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity
New inhibitors may reduce gut toxicity from cancer drugs.
research Optimization and validation of spectrophotometric methods for determination of finasteride in dosage and biological forms
The methods accurately measure finasteride in different forms.
research Untargeted hair lipidomics: comprehensive evaluation of the hair-specific lipid signature and considerations for retrospective analysis
research Sustained delivery of finasteride by biodegradable system
A biodegradable system can deliver finasteride consistently, reducing the need for daily pills.
research Disease-related biomarkers as experimental endpoints in 3D skin culture models
research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin
The drug was successfully released into hair follicles using nanocarriers.
research Sex Hormone-Binding Globulin as more than a Biomarker of Metabolic Diseases and Reproductive Disorders: What Physicians Should Know?
Low SHBG levels are linked to negative health outcomes and should be used in assessing and managing health conditions.
research QS8: Analysis of the Whole Transcriptome in Breast Cancer Patients Undergoing Radiotherapy and Breast Reconstruction
Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.
research Intestinal Permeability Study of Minoxidil: Assessment of Minoxidil as a High Permeability Reference Drug for Biopharmaceutics Classification
Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.
research Triggered release of model drug from AuNP-doped BSA nanocarriers in hair follicles using IRA radiation
Infrared light can trigger drug release from gold nanoparticle carriers in hair follicles.
research Abstract 4350: Pharmacodynamic biomarkers: Evaluation of oncology drug target engagement in human plucked scalp and beard hair
Plucked hair can effectively monitor drug effects in cancer treatment.
research Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control
Epristeride's metabolism in zebrafish helps improve doping detection methods.
research Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications
Microextraction techniques improve hormone testing while being environmentally friendly.
research EP-2271: The role of mitochondria in the non-targeted effect of ionizing radiation
Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.
research Assessment of biotin supplementation among patients in an outpatient dermatology clinic
Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
research Excretion of technetium in human milk
research The Bio-Safety Concerns of Three Domestic Temporary Hair Dye Molecules: Fuchsin Basic, Victoria Blue B and Basic Red 2
These temporary hair dyes may be harmful to human health.