research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
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360-390 / 1000+ results research Adjunctive treatment for leg ulcers
Different treatments help heal leg ulcers depending on their type, with new therapies showing promise for chronic wounds.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research Reconstitution of full-thickness skin by microcolumn grafting
Microcolumn grafting can effectively regenerate full-thickness, functional skin without scarring.
research Lidocaine-Loaded Solid Lipid Microparticles (SLMPs) Produced from Gas-Saturated Solutions for Wound Applications
Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
research Current and prospective strategies for advancing the targeted delivery of CRISPR/Cas system via extracellular vesicles
Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.
research Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment
WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.
research Acoustic Fabrication of Collagen–Fibronectin Composite Gels Accelerates Microtissue Formation
Ultrasound helps create gels that speed up tissue formation.
research RGDSP-functionalized peptide hydrogel stimulates growth factor secretion via integrin αv/PI3K/AKT axis for improved wound healing by human amniotic mesenchymal stem cells
A special hydrogel helps stem cells heal wounds better by boosting growth factors.
research Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages
Researchers used a laser to create advanced skin models with hair-like structures.
research In vitro hair follicle growth model for drug testing
Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
research Ficus benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation
Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.
research Platelet-rich plasma in interventional dermatology and trichology: How far have we come?
Platelet-rich plasma (PRP) shows promise in skin and hair treatments but results vary with preparation methods.
research Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair
Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.
research In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration
New methods to test hair growth treatments have been developed.
research Cold Atmospheric Plasma‐Activated In Situ Hydrogel Induces Hair Regeneration Via Immune Microenvironment Remodeling
The treatment using a special hydrogel shows promise for promoting hair growth.
research Hyperbranched polymer dots enhance hair follicle regeneration via Wnt/β-catenin activation: A drug-free nanozyme-based approach to hair growth therapy
Hyperbranched polymer dots significantly boost hair regrowth better than minoxidil.
research Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in the Non-mendelian Inheritance-Mediated Feather Growth Rate in Chicken
The research found specific genes and proteins that affect how fast chickens' feathers grow, which is not solely determined by traditional inheritance patterns.
research Bioengineering the Hair Follicle
Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
research Comparative Evaluation of Buffy Coat–Derived and Apheresis Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia: Laboratory and Clinical Insights
This study evaluated the effectiveness of two platelet-rich plasma (PRP) preparation methods, buffy coat and apheresis, in treating androgenetic alopecia (AGA) in 163 patients. Both methods significantly improved hair density and shaft diameter, with the buffy coat method showing a slight advantage in patient self-assessment, as 51.7% reported significant improvement compared to 46.1% in the apheresis group. Apheresis produced higher platelet concentrations and purity, while buffy coat had better platelet recovery efficiency. Despite apheresis's superior laboratory performance, the buffy coat method had a slight edge in patient-reported outcomes. The study highlights that factors beyond platelet count, such as growth factor release and platelet activation, are crucial for PRP efficacy. Limitations include a small sample size and lack of long-term follow-up, suggesting the need for larger trials and exploration of new regenerative approaches.
research Macrophage Related Chronic Inflammation in Non-Healing Wounds
Macrophage issues cause chronic wound inflammation, but therapies can help.
research Advances of Stem Cell Therapeutics in Cutaneous Wound Healing and Regeneration
Stem cells show promise in speeding up wound healing and tissue regeneration.
research Progress in Gelatin as Biomaterial for Tissue Engineering
Gelatin shows promise for future medical uses due to its safety and versatility, despite some challenges.
research Tissue engineering of skin and regenerative medicine for wound care
Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
research Bioactive inorganic particles‐based biomaterials for skin tissue engineering
Bioactive inorganic particles-based biomaterials show promise for improving skin wound healing.
research From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells
Oral stem cells show promise for tissue repair, but more human trials are needed.
research Nanomaterials-Based Wound Dressing for Advanced Management of Infected Wound
Nanomaterials in wound dressings help fight infections and improve healing.
research Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment
Controlling inflammation can help heal diabetic foot ulcers.
research Recent Advances in Biopolymeric Composite Materials for Tissue Engineering and Regenerative Medicines: A Review
Biopolymeric composites need advanced properties for better use in medicine and healing.
research Injectable Biomaterials for Dental Tissue Regeneration
Injectable biomaterials can effectively regenerate dental tissues.