research Sexual dysfunction with 5-alpha-reductase inhibitor therapy for androgenetic alopecia: a global propensity score matched retrospective cohort study
Taking medication for hair loss might cause sexual problems.
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research Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research Efficacy and safety of topical GT20029 in male patients with androgenetic alopecia: a multicenter, randomized, double-blind, placebo-controlled phase 2 study
Topical GT20029 effectively promotes hair regrowth and is well-tolerated for treating androgenetic alopecia.
research Design and selection of suitable niosomal formulation of finasteride by using different non-ionic surfactants
Formulation F1 is the best for delivering finasteride effectively.
research Histological evaluation of hair keratin based templates in mice
Keratin sponges are as biocompatible as collagen, but keratin gels are slightly less so.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Prodrugs of butyric acid from bench to bedside: Synthetic design, mechanisms of action, and clinical applications
New butyric acid prodrugs show promise for cancer treatment, anemia management, and protecting hair from chemotherapy damage.
research Repurposed Drugs: Current Trends in Drug Discovery
Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
research Evaluation of Sexual Function With an International Index of Erectile Function in Subjects Taking Finasteride for Androgenetic Alopecia
Finasteride for hair loss has minimal impact on sexual function.
research Measurement of the physicochemical, performance, and consumer-information characteristics of commercial nonmedicated shampoo for dogs
Commercial dog shampoos vary in quality and characteristics.
research PSS37 CATARACT SURGERY GUIDELINES IN EUROPE: A LITERATURE REVIEW AND DOCUMENT SEARCH IN 15 COUNTRIES
Cataract surgery guidelines vary across Europe, and generic finasteride sales for hair loss have grown due to pill splitting.
research [Systemic therapy of diffuse effluvium and hair structure damage].
Medication 1 improved hair quality and growth more effectively than medication 2 and the placebo.
research Harmonic Vibrational Frequency Simulation of Pharmaceutical Molecules via a Novel Multi-Molecular Fragment Interception Method
The new method provides more accurate vibrational frequencies for drug molecules than traditional models.
research Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium
One supplement improved hair loss and quality faster and more effectively than the other in treating telogen effluvium.
research LB1047 Comparative analysis of cutaneous hormonal profiles in pre-menopausal and post-menopausal women
Skin hormone levels change significantly after menopause.
research Ethosome as a potential transdermal drug delivery system
Ethosomes are a promising way to deliver drugs through the skin.
research Modeling the pharmacodynamics of nandrolone doping drug and implications for anti‐doping testing
The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.
research Comparing Adherence, Side Effects, and Satisfaction in Oral and Topical Minoxidil: A Cross-Sectional Study
Oral minoxidil is easier to use and more satisfying for hair loss treatment than topical minoxidil.
research Corrigendum to “Nitric oxide synergizes Minoxidil delivered by transdermal hyaluronic acid liposomes for multimodal androgenetic-alopecia therapy” [Bioact. Mater. 32 (2024) 190–205]
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Chromatographic method for clobetasol propionate determination in hair follicles and in different skin layers
A new method accurately measures clobetasol propionate in hair and skin.
research The influence of selected steroid hormones on the physicochemical behaviour of DPPC liposomes
Steroid hormones change the size, charge, and stability of DPPC liposomes.
research Development of a system for clinical evaluation of the biotin status of sows.
Serum biotin levels can indicate biotin deficiency in sows.
research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
research The “NOMINAL” trial: Clinical efficacy, cosmetic acceptability, and local tolerability of topical 5% minoxidil lotion without propylene glycol: A 6-month, multicentre, real-life, prospective, assessor-blinded study in 196 subjects with hair loss.
The 5% minoxidil lotion without propylene glycol is effective, well-tolerated, and cosmetically acceptable for hair loss.
research Comparative study of photobiomodulation and low frequency on the body contour: controlled, randomized, double blind clinical trial
Both photobiomodulation and low-frequency treatments effectively reduce body measurements.
research Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor
New hybrid compound found to effectively prevent hair loss.
research [Finasteride--ris of "unintentional doping"].
research Comparative Efficacy of Oral and Topical 5-Alpha Reductase Inhibitors in Reducing Dihydrotestosterone levels across Men with Androgenetic Alopecia: A Network Meta-Analysis incorporating Post-Hoc Analyses of Randomized Clinical Trial Data
Oral and topical 5-alpha reductase inhibitors affect DHT levels and hair density differently in treating hair loss.
research 695 Using MALDI-MSI analysis to study distribution of FOL-005, a potent, novel inhibitor of human hair growth, after subcutaneous injection in mice
FOL-005, a new substance, was found to reduce hair growth without toxicity when injected into skin, suggesting it could be used to treat excessive hair growth.