research Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation
Combining biomaterials and cell pathways can improve hair follicle regeneration.
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480-510 / 1000+ results research A Concise Review of Organoid Tissue Engineering: Regenerative Applications and Precision Medicine
Organoids can revolutionize medicine by modeling diseases and aiding in personalized treatments.
research 3D multicellular micropatterning biomaterials for hair regeneration and vascularization
The new biomaterial helps grow blood vessels and hair for skin repair.
research Developing Humanized Animal Models with Transplantable Human iPSC-Derived Cells
Humanized animal models using human stem cells can improve disease research and drug testing.
research Bioactive Compounds in Neurocosmetics: Bridging Nature-Derived Peptides and Synthetic Molecules for Advanced Skin Health and Well-being
Bioactive compounds in neurocosmetics can improve skin health and emotional well-being.
research Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research Wearable Bioelectronics for Chronic Wound Management
Wearable bioelectronics show promise for improving chronic wound care.
research ANÁLISES COMPUTACIONAIS PREDITIVAS COMO UM NOVO BIOPODER: MODIFICAÇÕES DO TEMPO NA SOCIEDADE DOS SENSORES
Predictive computational analyses have evolved biopower by using technology to track and predict individual and group behaviors.
research Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
The Aligned membranes improved wound healing and hair growth with a better immune response in mice.
research Precision and Personalized Medicine in Transdermal Drug Delivery Systems: Integrating AI Approaches
AI-enhanced smart patches can personalize drug delivery for better treatment outcomes.
research Biosynthesis of silver nanoparticles by endophytic fungi: Its mechanism, characterization techniques and antimicrobial potential
Silver nanoparticles made by fungi are eco-friendly and effective antimicrobials.
research Rejuvenation by Design: Building Cosmetic Products with Extracellular Vesicle Technology, the Example of Exo.Reset®
Exo.Reset® uses extracellular vesicle technology for skin rejuvenation.
research 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
3D bioprinting with special hydrogels helps heal wounds and grow new blood vessels.
research Regeneration of Human Hair Follicles by 3-D Bioprinting
3-D bioprinting can regenerate human hair follicles using bioink with collagen and fibroblasts.
research Life Sciences Discovery and Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations
Bioactive glasses help heal skin wounds by promoting tissue repair and preventing infections.
research Developing Patient-Derived 3D-Bioprinting models of pancreatic cancer
3D-bioprinting models of pancreatic cancer could help personalize treatments but need more testing.
research A guide to the use of bioassays in exploration of natural resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Rapid Formation of Cell Aggregates and Spheroids Induced by a “Smart” Boronic Acid Copolymer
A boronic acid copolymer quickly forms cell clusters, useful for tissue and tumor modeling.
research Skin Tissue-Engineering Constructs and Stem Cells Application for the Skin Equivalents Creation (Review)
The review says that stem cells are beneficial for making skin replacements.
research Grand challenges in dermatologic drug discovery: four priorities to transform skin disease treatment
Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
research Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling
This review discusses the advancement of hair follicle organoids towards immune-competent hair follicle microphysiological systems (HF-MPS), which aim to better replicate the immune, vascular, neural, and dynamic regulatory features of native hair follicles. These systems are particularly important for studying immune-mediated hair disorders like alopecia areata, where immune privilege collapse and inflammatory infiltration are key issues. The review outlines the structural basis of HF engineering and defines immune competence as maintaining immune privilege, regulating hair follicle cycling and regeneration, and managing inflammatory injury. It also explores engineering strategies such as local immune microenvironment control and dynamic perfusion. The applications of HF-MPS in disease modeling, drug evaluation, and regenerative medicine are discussed, emphasizing that these systems are evolving platforms rather than complete replacements for existing models.
research Herbal Nanocosmeceuticals: The Ultimate Fusion of Science and Nature
Herbal nanocosmeceuticals are more effective and eco-friendly than traditional skincare products.
research Structural Color of Partially Deacetylated Chitin Nanowhisker Film Inspired by Jewel Beetle
The film creates vibrant colors and can be used in food sensors and cosmetics.
research Scalable biofabrication and morphology evaluation of tissue spheroids
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
This study introduces a finite element analysis (FEA)-guided framework for designing separable bubble microneedles (BMNs) that optimize geometry and cavity parameters for controlled tip separation and robust insertion. The study tested minoxidil sulfate-loaded BMNs (MXS-BMNs) and insulin-loaded BMNs (INS-BMNs) for transdermal and sublingual delivery, respectively. The BMNs demonstrated effective payload release, with over 80% liberated within 10 minutes. In ex vivo tests, MXS-BMNs showed significantly higher minoxidil permeation compared to topical gel, and in vivo tests on mice showed accelerated hair regrowth. INS-BMNs effectively lowered glucose levels in diabetic rats, comparable to subcutaneous injections. This approach reduces empirical iteration, facilitating the development of efficient microneedle systems for rapid drug delivery.
research In vivo imaging: shining a light on stem cells in the living animal
New imaging technologies help us see how stem cells work in living animals.
research Human hair regeneration using organoids and hair-on-chip technologies
Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
research Regeneration of Peripheral Nerves Using Neuroinductive Biomaterial Scaffolds
Keratin biomaterials can effectively aid peripheral nerve regeneration and improve recovery.
research Editorial: Prevention and treatment of skin diseases
Personalized medicine and new technologies offer promising strategies for better skin disease treatments.