48 citations
,
September 2013 in “Oncologist” Endocrine therapies for cancer significantly increase the risk of hair loss.
47 citations
,
March 2022 in “Frontiers in cellular and infection microbiology” Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
47 citations
,
December 2020 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
47 citations
,
December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
47 citations
,
January 2019 in “Nature communications” Polyamines help fix DNA damage accurately in cells.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
47 citations
,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
45 citations
,
January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
41 citations
,
March 2007 in “Journal of dermatological science” Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
36 citations
,
January 2018 in “Scientific reports” Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.
36 citations
,
April 2016 in “British journal of dermatology/British journal of dermatology, Supplement” A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
33 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
32 citations
,
November 2011 in “International Journal of Dermatology” Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.
31 citations
,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
30 citations
,
October 2014 in “PLOS ONE” BAF200 is essential for proper heart and coronary artery formation.
30 citations
,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
29 citations
,
March 2008 in “Dermatologic Surgery” The Cross-section Trichometer is a new tool that can measure hair quantity and detect hair loss and growth.
29 citations
,
December 1998 in “Seminars in Cutaneous Medicine and Surgery” New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
28 citations
,
January 2021 in “Skin appendage disorders” COVID-19 may cause early hair loss similar to classic temporary hair loss, with further research needed.
26 citations
,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
26 citations
,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
22 citations
,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
20 citations
,
October 2021 in “PLoS ONE” Newborn skin is uniquely prepared to adapt to new environments compared to adult skin.
20 citations
,
October 2013 in “British Journal of Dermatology” The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
20 citations
,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
19 citations
,
March 2021 in “Obesity surgery” Many people experience hair loss after weight loss surgery, especially younger women, and it's linked to lower levels of zinc, folic acid, and ferritin.
19 citations
,
January 2012 in “Dermato-endocrinology” Moderately high prolactin levels do not cause hair loss in women.
18 citations
,
September 2023 in “Nutrition Research Reviews” Higher fiber intake may reduce psoriasis severity, but more research is needed for effective dietary strategies.
18 citations
,
September 2018 in “Experimental physiology” Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
17 citations
,
January 2013 in “Our Dermatology Online” Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.