6 citations
,
June 2024 in “Drug Testing and Analysis” Nails could be used to check long-term drug use, but more research is needed.
December 2023 in “Royal Society of Chemistry eBooks” Nails are a useful alternative to hair for analyzing long-term substance exposure.
September 2014 in “Emergency Medicine News” The man's skin condition improved with sun protection and topical steroids, but UV exposure still caused flare-ups.
September 2024 in “Journal of the American Academy of Dermatology” April 2016 in “Journal of the American Academy of Dermatology”
42 citations
,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
139 citations
,
October 2005 in “Journal of Investigative Dermatology” The nail matrix has a reduced immune response, protecting it from autoimmunity.
22 citations
,
October 2007 in “Journal of Investigative Dermatology” Stem cells in mouse nails are found in the nail matrix and may control nail growth.
1 citations
,
January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
6 citations
,
May 2024 in “Developmental Biology”
8 citations
,
April 2017 in “International Journal of Dermatology” Applying 5% minoxidil to fingernails can significantly increase their growth rate.
January 2014 in “Pathology” The document concludes that understanding nail anatomy is key for diagnosing nail diseases, early signs of nail melanoma may allow for less aggressive treatment, and specific genetic mutations are important in thyroid cancer prognosis and treatment.
March 2025 in “Dermatology” Systemic therapies improve nail psoriasis but have high side effects; more research is needed.
Nail stem cells help nail and finger regeneration through BMP signaling.
6 citations
,
July 1975 in “Archives of Dermatology” Rapid weight loss from dieting and hormonal injections can cause significant hair loss in women.
1 citations
,
February 1977 in “Archives of Dermatology” Fresh plasma transfusions did not help treat Leiner disease in an infant.
November 2025 in “Cermin Dunia Kedokteran” A 16-year-old girl with autoimmune hemolytic anemia and deep vein thrombosis improved with treatment, possibly indicating systemic lupus erythematosus.
March 2014 in “Journal of The American Academy of Dermatology” Reflectance confocal microscopy can noninvasively diagnose onychomatricoma by showing unique features different from healthy nails or nail fungus.
September 2009 in “Medical and surgical dermatology/Medical & surgical dermatology”
3 citations
,
October 2021 in “Cureus” Smoking can cause yellow discoloration of upper lip hair and nails.
119 citations
,
January 2000 in “British Journal of Dermatology” Different parts of the nail express different keratins, showing unique patterns of differentiation.
30 citations
,
January 2013 in “Human Mutation” A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.
23 citations
,
February 1993 in “Journal of Investigative Dermatology”
January 2014 in “Pathology” Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
7 citations
,
September 2011 in “International Journal of Dermatology” The Korean study found that twenty-nail dystrophy mainly affects adults, more often women, and has five distinct types with different clinical progressions.
May 2015 in “Journal of The American Academy of Dermatology” The treatments for fungal nail infection, hair loss in men, benign nail tumor, and chemotherapy-associated nail bed inflammation are effective and safe.
2 citations
,
September 2015 in “Türk pediatri arşivi : İstanbul çocuk kliniği dergisi” Valproic acid can very rarely cause nail separation, which usually gets better on its own after stopping the drug.
September 2023 in “Journal of Cosmetic Dermatology” Minoxidil, a hair loss treatment, may help nails grow faster.
2 citations
,
June 2024 in “Journal of Clinical Medicine” Alopecia Areata can affect nails, often improving on its own, but JAK inhibitors may help.
January 2015 in “Dermatology online journal” A man with total hair loss also developed a rare nail condition, likely due to autoimmune issues.