June 2026 in “Strathprints: The University of Strathclyde institutional repository (University of Strathclyde)” The study investigates NF-κB signalling in CYLD cutaneous syndrome (CCS) tumours to identify potential drug targets. Researchers used transcriptomics, proteomics, and single-cell RNA sequencing on patient-derived CCS tumour cells, revealing evidence of non-canonical NF-κB signalling with increased p100 to p52 processing and RelB protein expression. IκB kinase alpha (IKKα) was identified as a candidate target, and a novel IKKα inhibitor (SU1644) was tested on CCS tumour spheroid cultures, showing reduced tumour viability. The findings support the potential use of topical IKKα inhibitors as a preventive treatment for CCS.
3 citations
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August 2023 in “Biophysical Journal” Mitochondrial activity varies in cells before they stop growing, affecting their growth potential.
5 citations
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August 2025 in “Drug Delivery and Translational Research” Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.
1 citations
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June 2007 in “Journal of Clinical Oncology” Weekly bicalutamide is safe and effective, with 50 mg/week recommended.
80 citations
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April 2017 in “Frontiers in Pharmacology” PDRN helps repair tissue and improve wound healing with a high safety profile.
August 2025 in “Skin Research and Technology”
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain genetic variants in ERN1, TACR3, and SPPL2C are linked to when Alzheimer's disease starts.
January 2009 in “Bradford Scholars (University of Bradford)” BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.
15 citations
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January 2020 in “ILAR Journal” Nonhuman primates are valuable in research but their natural health variations can complicate study results.
The protein's size was reduced, but more work is needed to confirm its function.
2 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The SYP123-VAMP727 complex is important for transporting materials that harden the root hair shank in Arabidopsis.
1 citations
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July 2025 in “Scientific Reports” CD133+ cells are crucial for hair growth.
January 2025 in “Online Publication Service of Würzburg University (Würzburg University)” A protocol was developed to create 3D skin models from adult diseased cells to study Small Fiber Neuropathy.
7 citations
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March 2019 in “Medicine” Combining light therapy and microneedling shows promise for treating female hair loss.
April 2025 in “Turkish Journal of Hematology” Nilotinib may cause gray hair to return to its original color.
January 2000 in “Europe PMC (PubMed Central)” 15 citations
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March 1996 in “PubMed” Anorexia nervosa may cause a hair defect called pili torti due to malnutrition and high vitamin A levels.
8 citations
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September 2019 in “Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity” A woman with anorexia nervosa improved after treatment for pellagra, reminding doctors to check for this deficiency in patients with eating disorders.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Ixekizumab may be an effective first treatment for a rare skin condition causing hair loss.
Early biotin treatment can reverse symptoms of congenital biotinidase deficiency.
36 citations
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September 2015 in “Forensic Science International: Genetics” Certain DNA variants can predict straight hair in Europeans but are not highly specific.
26 citations
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May 1984 in “Journal of Parenteral and Enteral Nutrition” Biotin supplements restored hair and resolved symptoms in a woman with biotin deficiency.
1 citations
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August 2021 in “Journal of The American Academy of Dermatology” Baricitinib helped improve hair, eyebrow, and eyelash growth in alopecia areata patients.
May 2024 in “Frontiers in medicine” A genetic mutation in the LIPH gene causes tightly curled hair that stops growing in some Japanese individuals.
January 1990 in “대한피부과학회지” Peanut agglutinin staining helps differentiate malignant melanoma from nevocellular nevus.
1 citations
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July 2023 in “Cureus” A rare hair disorder with multiple hairs from one follicle was found on a patient's abdomen.
9 citations
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January 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study explores miRNA changes in female hair loss.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study explores miRNA changes in female hair loss.
January 2016 in “프로그램북(구 초록집)” The thulium laser and PDRN injections effectively improved hair thickness in patients with pattern hair loss.