February 2025 in “Science Advances” Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
10 citations
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August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
488 citations
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July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
75 citations
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September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
15 citations
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March 2021 in “Journal of Nanobiotechnology” A new method was developed to grow and maintain human hair follicle stem cells for hair reconstruction.
10 citations
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May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
8 citations
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October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
5 citations
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February 2014 in “PloS one” Eyelid cells share signaling components but differ in pathway activity.
1 citations
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November 2023 in “Medicina” Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
December 2025 in “Animals” TGFBR1 slows down cell growth in fine-wool sheep hair follicles.
October 2025 in “Journal of Nanobiotechnology” The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
16 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
8 citations
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January 2014 in “Journal of Stem Cell Research & Therapy” Stem cell therapy improves healing and reduces pain in cutaneous radiation syndrome.
March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
11 citations
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July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
January 2026 in “Frontiers in Pharmacology” Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
245 citations
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
72 citations
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November 2020 in “Frontiers in Surgery” L-PRF may help bone growth and healing, but more research is needed.
3 citations
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September 2021 in “JAAD case reports” Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.
December 2024 in “Advanced Composites and Hybrid Materials” Electrospun 3D nanofibrous materials show promise for bone regeneration in orthopaedics.
14 citations
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July 2021 in “Bioscience Reports” Activating Tgr5 may help treat hair loss and bone loss.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
40 citations
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” Changes in keratin make hair follicles stiffer.
January 2014 in “Pathology” Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
July 2011 in “Microscopy and microanalysis” Human hair's structure makes it tough and resistant to breaking.
2 citations
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January 2008 in “Elsevier eBooks” Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
291 citations
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April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.