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GlossaryMesenchymal Stem Cells

cells that can become bone, cartilage, or fat cells

Mesenchymal Stem Cells (MSCs) are a type of multipotent stem cell found in various tissues, including bone marrow, fat, and umbilical cord tissue. They have the ability to differentiate into a variety of cell types, such as bone, cartilage, and fat cells, making them valuable for regenerative medicine and tissue engineering.

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research Study on the regulatory effect of Panax notoginseng saponins combined with bone mesenchymal stem cell transplantation on IRAK1/TRAF6-NF-κB pathway in patients with diabetic cutaneous ulcers

10 citations , January 2023 in “Journal of Orthopaedic Surgery and Research”

Panax notoginseng saponins with stem cells improve healing and reduce inflammation in diabetic ulcers.

research Comparative characterization and osteogenic / adipogenic differentiation of mesenchymal stem cells derived from male rat hair follicles and bone marrow

6 citations , August 2020 in “Cell regeneration”

Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.

research Topical Transplantation of Bone Marrow Mesenchymal Stem Cells Made Deeper Skin Wounds Regeneration

October 2020 in “Plastic Surgery”

Bone marrow stem cells improve healing of deep skin wounds.

research TMT-Based Quantitative Proteomic Analysis Reveals the Effect of Bone Marrow Derived Mesenchymal Stem Cell on Hair Follicle Regeneration

4 citations , June 2021 in “Frontiers in Pharmacology”

Bone marrow stem cells and their medium help hair regrowth.

Transplantation of Bone Mesenchymal Stem Cells Effectively Promotes Intestine Regeneration to Eliminate Endotoxemia and Reduce Mortality in the Animal Model of Acute Liver Failure

research Transplantation of bone mesenchymal stem cells effectively promotes intestine regeneration to eliminate endotoxemia and reduce mortality in the animal model of acute liver failure

May 2020 in “Research Square (Research Square)”

Bone marrow stem cells help heal intestines and reduce death in liver failure.

research Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

139 citations , May 2020 in “Stem Cell Research & Therapy”

Exosomes from stem cells help wounds heal faster by affecting specific cell signals.

research [Influence of the stiffness of three-dimensionally bioprinted extracellular matrix analogue on the differentiation of bone mesenchymal stem cells into skin appendage cells].

3 citations , November 2020 in “PubMed”

Stiffer hydrogels better promote stem cells turning into hair follicle cells.

research Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells

151 citations , February 2006 in “Stem Cells and Development”

Hair follicles can be a good source of stem cells like those from bone marrow.

research Application of mesenchymal stem cells derived from bone marrow and umbilical cord in human hair multiplication

41 citations , September 2010 in “Journal of dermatological science”

Bone marrow and umbilical cord stem cells can help grow new hair.

research Differentiation Potential Analysis of Bone Marrow Mesenchymal Stem Cells from Guizhou Miniature Pigs

1 citations , January 2024 in “Advances in Engineering Technology Research”

Bone marrow stem cells from Guizhou miniature pigs can grow well and become different cell types, useful for tissue engineering.

research Human bone marrow mesenchymal stem cells-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

1 citations , May 2020 in “Research Square (Research Square)”

Exosomes from stem cells help wounds heal faster by affecting specific cell signals.

research The Research on Bone Marrow Mesenchymal Stem Cells Repairing Rabbit Skin Wound Defect

January 2005 in “Journal of Nanhua University”

Bone marrow mesenchymal stem cells help rabbit skin wounds heal faster.

Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features

research Transplantation of bone-marrow-derived mesenchymal and epidermal stem cells contribute to wound healing with different regenerative features

36 citations , April 2013 in “Cell and Tissue Research”

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

research Faculty Opinions recommendation of Application of mesenchymal stem cells derived from bone marrow and umbilical cord in human hair multiplication.

November 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Mesenchymal stem cells from bone marrow and umbilical cord can help regenerate hair follicles.

research Histological study of the effect of bone marrow-derived mesenchymal stem cells on healing of skin defect in adult male albino rats

2 citations , March 2014 in “The Egyptian Journal of Histology”

Bone marrow-derived stem cells greatly improve skin wound healing in rats.

research Pengaruh Pemberian Human Bone Marrow Mesenchymal Stem Cell Terhadap Gambaran Mikroskopis Jaringan Adneksa Pada Kulit Tikus Luka Bakar Diabetes Melitus

1 citations , November 2022 in “Jurnal Ilmu Kesehatan Indonesia”

Human bone marrow stem cells increased skin tissue growth in diabetic rats with burns, but not significantly.

research “Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine”

1 citations , November 2024 in “Bone Reports”

Cellularity can estimate mesenchymal stem cell concentration in bone marrow, aiding regenerative medicine.

research Intravenous Transplantation of Human Hair Follicle-Derived Mesenchymal Stem Cells Ameliorates Trabecular Bone Loss in Osteoporotic Mice

8 citations , March 2022 in “Frontiers in Cell and Developmental Biology”

Human hair follicle stem cells can help treat bone loss in osteoporosis.

research Osteogenic Potential of Mesenchymal Stem Cells from Adipose Tissue, Bone Marrow and Hair Follicle Outer Root Sheath in a 3D Crosslinked Gelatin-Based Hydrogel

2 citations , May 2021 in “International journal of molecular sciences”

Stem cells from hair follicles in a special gel show strong potential for bone regeneration.

research C53 HAIR FOLLICLE STEM CELLS AND BONE MARROW MESENCHYMAL STEM CELLS IN BLADDER REGENERATION

1 citations , September 2010 in “European Urology Supplements”

Adipose-Derived Stem Cell Exosomes Promote Critical-Sized Bone Defect Repair by Enhancing the Homing of Bone Marrow Mesenchymal Stem Cells

research Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells

January 2026

Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.

research Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway

18 citations , January 2013 in “Evidence-based Complementary and Alternative Medicine”

Aconiti Lateralis Preparata Radix helps mouse stem cells grow and turn into bone cells faster than usual methods.

research The Effect of Spirulina Algae (Arthrospira platensis) Extract on the Differentiation of Bone Marrow Derived Mesenchymal Stem Cells to Neuron Cells

July 2025 in “Bulletin de la Banque Méllié Iran.”

Spirulina extract helps stem cells become neuron cells safely.

research The effect of resveratrol on the viability of rat bone marrow mesenchymal stem cells

November 2024 in “Clinical Nutrition Open Science”

High doses of resveratrol improve bone cell health and differentiation.

research Irradiation by high-intensity red light-emitting diode enhances human bone marrow mesenchymal stem cells osteogenic differentiation and mineralization through Wnt/β-catenin signaling pathway

April 2021 in “Institutional Repositories DataBase (IRDB)”

High-intensity red LED light boosts bone cell growth and mineralization.

research Current Advanced Therapies Based on Human Mesenchymal Stem Cells for Skin Diseases

48 citations , March 2021 in “Frontiers in Cell and Developmental Biology”

Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.

Management of Female Pattern Hair Loss Using Autologous Mesenchymal Stem Cells: Report of Two Cases

research Management Of Female Pattern Hair Loss (FPHL) Using Autologous Mesenchymal Stem Cells : Report Of Two Cases

January 2026 in “Annals of dermatological science.”

Stem cells can effectively regrow hair in women with hair loss.

Therapeutic Effect of Mesenchymal Stem Cells on Histopathological, Immunohistochemical, and Molecular Analysis in Second-Degree Burn Model

research Therapeutic effect of mesenchymal stem cells on histopathological, immunohistochemical, and molecular analysis in second-grade burn model

10 citations , May 2021 in “Stem Cell Research & Therapy”

Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.

Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin

research Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin

43 citations , December 2013 in “Stem Cells”

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

research Comparative transcriptomic analysis of human mesenchymal stem cells derived from dental pulp and adipose tissues

8 citations , May 2019 in “Journal of Stem Cells & Regenerative Medicine”

Dental pulp stem cells are better for tissue repair, while fat tissue stem cells may be more suited for wound healing and hair growth.