February 2026 in “Human Cell” MSC-CM can boost skin cell growth and movement, aiding skin repair.
158 citations
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August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
15 citations
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January 2010 in “Experimental Dermatology” Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
133 citations
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May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
32 citations
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July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
28 citations
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October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
25 citations
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August 2017 in “Animal Biotechnology” Researchers found that certain RNA molecules might play a role in the growth of Cashmere goat hair.
18 citations
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July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.
333 citations
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
October 2025 in “Frontiers in Veterinary Science” Quercetin boosts hair follicle stem cell growth and survival in cashmere goats.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
1066 citations
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March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
773 citations
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August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
667 citations
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May 2008 in “Genes & Development” Histone demethylases can change gene expression and may be linked to diseases like cancer.
556 citations
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September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
480 citations
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August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
256 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
137 citations
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
108 citations
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July 2004 in “American Journal of Pathology” Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
70 citations
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February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
54 citations
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October 2023 in “Oncogene” p63 is essential for controlling epithelial stem cells and tissue health.
45 citations
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April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
42 citations
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February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
41 citations
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December 2019 in “Stem Cell Reviews and Reports” Tooth regeneration could become possible by controlling how and when bioactive factors are released.
35 citations
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April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
29 citations
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March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.