240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
8 citations
,
May 2018 in “The Journal of Allergy and Clinical Immunology” Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
59 citations
,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
45 citations
,
October 2014 in “Stem cell research & therapy” Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.
42 citations
,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
27 citations
,
May 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
15 citations
,
July 2020 in “Stem Cell Research & Therapy” Stem cell therapy helps heal burn wounds, especially second-degree burns, by promoting blood vessel growth and reducing inflammation.
14 citations
,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
6 citations
,
January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
14 citations
,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
4 citations
,
September 2024 in “Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics” 3D models and organoids improve liposarcoma research and therapy development.
3 citations
,
September 2018 in “Journal of Biomaterials Science, Polymer Edition” Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.
150 citations
,
December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
124 citations
,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
85 citations
,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
43 citations
,
January 2012 in “Biological Research” The origins of many adult skin stem cells are still mostly unknown.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
8 citations
,
April 2023 in “Cureus” Stem cells could be a better treatment for hair loss by reactivating dormant hair follicles.
1 citations
,
September 2023 in “Journal of Fatwa Management and Research” Islamic perspectives in Malaysia raise ethical concerns about using stem cells, especially from embryos, for beauty and medical treatments.
August 2019 in “Regenerative Medicine” In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.
6 citations
,
May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
10 citations
,
November 2019 in “Cold Spring Harbor Perspectives in Biology” Stem cells are more dynamic and adaptable than previously believed.
2 citations
,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
1 citations
,
June 2010 in “Development” The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
March 2026 in “Frontiers in Cell and Developmental Biology” Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
2 citations
,
June 2023 in “Gels” Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
42 citations
,
August 2008 in “Stem Cells and Development” Hair follicle cells can help regenerate teeth.