research Thiohydrazides in the Synthesis of Functionalized Extranuclear Heterosteroids
New steroid derivatives show promise as anticancer agents, even against resistant cells.
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450-480 / 1000+ resultsresearch Angiosarcoma of the Scalp Mimicking an Inflammatory Scarring Alopecia and Diagnosed on Horizontal Histologic Sections
Rare skin cancer can mimic hair loss conditions, so thorough diagnosis is crucial.
research Notes from the Editor Emeritus: Finasteride: the downtrodden hero of hair transplantation emerges once again
Finasteride is effective for hair loss but has controversial side effects.
research Diseases of the Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
research How to Deal with the Issues of Fertility, Malignancies, and the Postfinasteride Syndrome while Prescribing Finasteride for Male Pattern Hair Loss
Finasteride is effective for male hair loss, but it may cause fertility issues, mental health problems, and rarely, breast growth. Regular health checks can reduce the risk of prostate cancer. Patient understanding and involvement in treatment is important.
research Post-Finasteride Syndrome (PFS) Update: Point/Counterpoint
Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.
research Non-Contraceptive Benefits of Oral Hormonal Contraceptives
Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.
research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
research Outcomes in Clinically Relevant Patient Subgroups From the EMBRACA Study: Talazoparib vs Physician’s Choice Standard-of-Care Chemotherapy
Talazoparib is more effective than standard chemotherapy for advanced breast cancer with BRCA mutations.
research Aesthetic medicine treatments for oncology patients — a narrative literature review
Aesthetic treatments can safely improve cancer patients' quality of life with oncologist approval.
research The antiandrogenic effect of finasteride against a mutant androgen receptor
Finasteride may improve prostate cancer treatment outcomes.
research Alarmin Cytokines as Central Regulators of Cutaneous Immunity
Alarmin cytokines are key in controlling skin immunity and inflammation.
research Intracellular Calcium Mobilization in Response to Ion Channel Regulators via a Calcium-Induced Calcium Release Mechanism
Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.
research Recent advances in understanding of radiation-induced skin tissue reactions with respect to acute tissue injury and late adverse effect
Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
research Endocrine intervention for transsexuals
Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
research A systematic review of antiandrogens and feminization in transgender women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research Tumor Angiogenesis and Anti-angiogenic Therapy
Anti-angiogenic therapy can help treat cancer but may cause resistance and side effects, so alternative methods are being explored.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
research Provenge is Talk of GU Malignancies Congress
Provenge extends prostate cancer survival by about 4 months.
research Protoporphyrin IX: the Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Targeted radionuclide therapy for head and neck squamous cell carcinoma: a review
Targeted radionuclide therapy shows promise for improving head and neck cancer treatment but needs more research.
research Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
research Oncogenic senescence: a multi-functional perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research Efficacy of albumin-bound paclitaxel combined with nedaplatin in neoadjuvant therapy for esophageal squamous cell carcinoma: A single-center retrospective observational study
The combination therapy is effective and well-tolerated for treating esophageal cancer.
research Dermoscopy of neoplastic alopecia secondary to cutaneous metastasis from breast carcinoma
Recognizing specific scalp patterns can help diagnose hair loss linked to breast cancer spread.
research Therapeutic Potential of Brassinosteroids in Biomedical and Clinical Research
Brassinosteroids may be useful in treating cancer, infections, and other diseases.
research Formulation of chloroaluminum phthalocyanine incorporated into PS-b-PAA diblock copolymer nanomicelles
The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
research Medical Treatment of Hepatocellular Carcinoma: Any Progress?
As of 1994, treatments for liver cancer had not significantly improved patient survival.
research Metformin and Malignant Tumors: Not Over the Hill
Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.