15 citations
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January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
22 citations
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April 2013 in “Dermatologic surgery” Bimatoprost effectively and safely improves eyebrow appearance.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” BMP signaling controls hair growth and skin color.
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” Latanoprost therapy potentially caused a woman's white hair to darken again.
11 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
1 citations
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January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
June 2025 in “Clinical and Experimental Dermatology” Baricitinib treatment led to dark brown hair regrowth in a red-haired woman with alopecia areata.
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April 1979 in “Journal of Ultrastructure Research”
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May 2012 in “Clinical and Experimental Dermatology” An 82-year-old woman's hair turned white suddenly, likely due to a rare form of alopecia that targets pigmented hair.
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September 2017 in “General and comparative endocrinology” Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
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September 1997 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in mice causes hair loss and skin issues due to a defect in a gene affecting cell adhesion.
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
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September 2021 in “Data in brief” Bleaching hair changes its structure and weakens it, which is important for understanding hair damage and creating treatments.
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January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
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January 2016 in “Evidence-based Complementary and Alternative Medicine” Rice bran extract can increase melanin production and may help treat melanin deficiency.
April 1986 in “CRC Press eBooks” Hair color is determined by melanins produced in hair cells.
Heated radish extract may help lighten skin and reduce aging signs.
56 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
22 citations
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September 2004 in “Journal of The European Academy of Dermatology and Venereology” Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
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October 2010 in “Molecular Imaging and Biology” Increased skin pigmentation in mice reduces bioluminescent signal accuracy.
January 2022 in “SSRN Electronic Journal” Mouse hair follicles age, causing more white hairs due to fewer pigment stem cells.
PMEE may help reverse greying hair by boosting melanin production.
16 citations
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February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
September 2021 in “CRC Press eBooks” Pregnancy can cause normal skin changes, including darkening of certain areas, nail changes, vascular changes, and breast changes like stretch marks.
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March 2009 in “Skin pharmacology and physiology” Sunlight damages hair, causing cuticle loss, protein changes, and discoloration.
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September 2024 in “Quality in Sport” Hair graying can be delayed or prevented with antioxidants, lifestyle changes, and genetic therapy.
June 2024 in “British Journal of Dermatology” Vitamin B supplements may reverse grey hair.
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January 2009 in “International Journal of Trichology” Sunlight exposure ages hair, making it brittle, stiff, and dry.
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
MITF and WNT3A are key in Dun Mongolian horse pigmentation.