research Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle
Sox10 is important for hair follicle development and hair growth cycles.
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research K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors
NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus
The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.
research Isolation and Characterization of Cutaneous Epithelial Stem Cells
Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
research Identification of the Novel Membrane-Associated Protein AgK114 on Hamster Keratinocytes Recognized by a Monoclonal Antibody K114
AgK114 protein helps in hamster skin injury recovery.
research Effects of gamma rays on the regeneration of murine hair follicles in the natural hair cycle
Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
research Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
research Aging of hair follicle stem cells and their niches
Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
research Tissue homeostasis
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Mechanism of Apoptotic Regulation of Follicular Regression
The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
research Evaluation of Two Medium-Depth Peels: Glycolic Acid 70% Versus Trichloroacetic Acid 35%: A Histological and Immunohistochemichal Study on Rat Skin
Both TCA and GA peels effectively improved skin thickness and collagen without significant differences.
research Activation of Bulge Stem Cells through Mechano-Stimulation and ECM Remodeling: Emerging Paradigms in Hair Follicle Regeneration
research 1360 Regulation of bmp signalling in melanogenesis, pigment transfer and melanocyte migration
BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
research An Investigation of Keratin 15 Function by Small Interfering Ribonucleic Acid Technology
Keratin 15 affects cell behavior and characteristics in skin cells.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Follicular Stem Cells in Androgenetic Alopecia
Hair loss in Androgenetic Alopecia is not caused by damage to follicular stem cells.
research Structures of three polycystic kidney disease-like domains fromClostridium histolyticumcollagenases ColG and ColH
The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
research The HPV16 oncogenes cause aberrant stem cell mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research Telocytes in human skin – are they involved in skin regeneration?
Telocytes might help with skin repair and regeneration.
research Dissecting the bulge in hair regeneration
Stem cells in hair follicles are diverse and change throughout the hair cycle.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Krox20 in epithelial and glial stem cells and their niches
Krox20 is important for cell differentiation in the brain and hair follicles.
research Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34
CD34 is a marker for isolating stem-like cells in mouse hair follicles.
research Emerging interactions between skin stem cells and their niches
Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
research Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons
Hair-follicle stem cells can become neurons.
research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
research Melanocytes: The new Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.