4 citations
,
January 2013 in “Stem cell discovery” Researchers created a cell line from a hair follicle to study hair loss.
3 citations
,
April 2012 in “Cancer research” Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.
2 citations
,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
2 citations
,
December 2011 in “[Thesis]. Manchester, UK: The University of Manchester; 2011.” Immune system failure in hair follicles causes lichen planopilaris, leading to hair loss.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” 7DHC and BM15766 damage hair follicle structure and reduce key gene expression.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
September 2024 in “British journal of surgery” Autologous stem cell therapy may effectively increase hair density in Androgenetic Alopecia.
July 2024 in “British journal of surgery” Stem cell therapy shows promise for treating hair loss.
January 2019 in “Publisher” Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.
Alopecia areata is reversible because hair follicles can regenerate due to stem cells.
June 2015 in “The American journal of dermatopathology/American journal of dermatopathology” The study found that a one-step antibody method is better than the LSAB method for accurately studying hair follicle structures without false positives.
March 2014 in “Anais Brasileiros de Dermatologia” Hair follicles are a key source of stem cells for skin repair and could help treat baldness.
February 2012 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” A new imaging technique can observe stem cells in living mice without harming them.
Laser hair removal may cause skin changes that prevent hair regrowth.
September 2017 in “Journal of Investigative Dermatology” Photodynamic therapy can potentially remove nonpigmented hair by damaging hair follicles.
May 2015 in “Hair transplant forum international” Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
105 citations
,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
20 citations
,
April 2009 in “Cell Biology International” Hair follicle stem cells can become corneal-like cells with the help of pax6.
19 citations
,
April 2016 in “Experimental Dermatology” Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
4 citations
,
August 2017 in “International journal of molecular sciences” The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.
3 citations
,
January 2023 in “JEADV Clinical Practice” IL-17 is more important than IFN-γ in causing severe hair loss in chronic alopecia areata.
2 citations
,
August 2012 in “Cell Stem Cell” The study showed that some hair follicle stem cells wake up to grow hair while others stay asleep, and that the environment around them is important for hair growth.
2 citations
,
June 2001 in “American Journal of Pathology” The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
January 2015 in “Faculty of 1000 Research Ltd” Androgenetic alopecia may be irreversible due to the detachment of a muscle from hair follicles.
Hair follicle stem cells can be cultured, but better methods are needed for longer growth.
January 2012 in “Chinese Journal of Aesthetic Medicine” Increased androgen receptor expression in certain hair follicle areas may cause male pattern baldness.
January 2012 in “대한미용학회지” Hair follicle stem cells can be cultured, but improvements are needed for longer growth.