132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
10 citations
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September 2022 in “Cellular and Molecular Life Sciences” SOX9 is essential for the development of various organs and hair follicles.
January 2026 in “Journal of Biosciences and Medicines” Androgenetic alopecia treatments focus on reducing hair loss by targeting hormones, with new therapies showing promise but needing more research.
April 2025 in “International Journal of Molecular Sciences” New treatments for hair loss show promise with advanced therapies and better targeting.
March 2025 in “Aging Cell” Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
April 2017 in “Journal of Investigative Dermatology” The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
December 2025 in “Pharmaceutics” Personalized skin rejuvenation using genomics shows promise but needs more research.
5 citations
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April 2022 in “Pharmaceutics” Minoxidil nanoparticles significantly boost hair growth in mice compared to regular minoxidil.
3 citations
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September 2025 in “Cosmetics” Extracellular vesicles could revolutionize skincare by improving skin repair and anti-aging, but face regulatory and cost challenges.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
83 citations
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October 2016 in “Stem Cells and Development” Epidermal growth factor helps hair stem cells grow by activating specific cell pathways.
9 citations
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June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
12 citations
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December 2010 in “Burns” P-auricular skin is the best donor site for high stem cell content in keratinocyte cultures.
89 citations
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September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
170 citations
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July 2012 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
3 citations
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November 2022 in “Frontiers in molecular biosciences” Plasmalogens activate a channel in cells that may stimulate hair growth.
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
7 citations
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January 2020 in “Nature” Stress turns hair white by depleting color-giving cells in hair follicles through a specific neurotransmitter related to the body's stress response.
December 2012 in “Journal of dermatological science” Hair follicles help attract immune cells to minor skin injuries.
72 citations
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April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
30 citations
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March 2015 in “PLoS ONE” Thyroxine can adjust the body's peripheral clock, potentially helping treat clock-related diseases.
17 citations
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February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
17 citations
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January 2013 in “Journal of Cosmetics, Dermatological Sciences and Applications” 3D bioprinting could improve skin repair and treat conditions like vitiligo and alopecia by precisely placing cells.
788 citations
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February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
27 citations
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June 2023 in “Nature” Senescent melanocytes can boost hair growth by activating hair stem cells.
18 citations
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April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.