6 citations
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March 2007 in “BioTechniques” PCR genotyping in cre-loxP mice can be inaccurate due to unintended gene deletions in non-target tissues.
January 2026 in “MDPI (MDPI AG)” The hairy ear mutation in mice is linked to changes in gene expression affecting hair growth.
52 citations
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October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
July 1993 in “Journal of Radioanalytical and Nuclear Chemistry” Mouse hair element patterns vary, making it unreliable for tracking time.
89 citations
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August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
62 citations
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April 2008 in “Neurobiology of aging” Scientists found a gene in mice that causes early hearing loss.
8 citations
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January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
111 citations
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March 1951 in “Annals of the New York Academy of Sciences” Understanding the mouse hair cycle is crucial for cancer research.
8 citations
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March 2014 in “American Journal of Pathology” Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
Suppressing ODC activity reduces tumor growth in hair follicles.
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
37 citations
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June 2000 in “Experimental dermatology” The Lanceolate hair-J mutation in mice mimics human hair disorders like Netherton's syndrome.
15 citations
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July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
25 citations
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March 2004 in “Regulatory Toxicology and Pharmacology” Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
231 citations
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October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
Meis2 is essential for touch sensation and nerve function in mice.
5 citations
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September 2022 in “Journal of Investigative Dermatology” Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.
118 citations
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June 1993 in “Journal of Biological Chemistry” Human and mouse TGase3 enzymes are similar but differ near the activation site, crucial for their function in skin and hair development.
40 citations
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November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
28 citations
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June 1994 in “Journal of Dermatological Science” Proteolytic activity in mouse skin changes with hair cycle stages, peaking in early anagen.
165 citations
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September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
1 citations
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December 2014 in “Zenodo (CERN European Organization for Nuclear Research)” The method effectively induces skin cancer in mice for studying tumor development.
13 citations
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November 2012 in “PLoS ONE” A gene mutation in mice causes severe skin disorder similar to a human condition.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
Hedgehog signaling can create new hair follicles but may also cause tumors.
December 2024 in “European journal of medical research” 10 citations
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January 2004 in “Journal of Investigative Dermatology” Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.
January 2010 in “Acta Laboratorium Animalis Scientia Sinica” The UHS promoter is specific to mouse hair follicles.
153 citations
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November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
14 citations
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July 1994 in “Journal of Investigative Dermatology”