32 citations
,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
31 citations
,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
26 citations
,
December 2009 in “Laser Physics” Caffeine from shampoo penetrates hair follicles quickly and stays for at least 24 hours.
24 citations
,
February 2007 in “Laser Physics Letters” Caffeine shampoo penetrates hair follicles deeply and stays for up to 48 hours.
21 citations
,
September 1966 in “Toxicology and Applied Pharmacology” Caffeine becomes more toxic in rats when food intake is reduced by over 50%.
18 citations
,
May 2023 in “Preprints.org” Caffeine can boost health but may cause side effects like high blood pressure and migraines.
17 citations
,
October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
15 citations
,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
15 citations
,
June 1996 in “Journal of Pharmacy and Pharmacology” Caffeine levels in hair and blood can indicate liver health.
12 citations
,
April 2020 in “British Journal of Dermatology” Caffeine may help reduce stress-induced hair loss.
11 citations
,
July 2012 in “International Journal of Trichology” Caffeine may help hair growth in hereditary hair loss.
10 citations
,
July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
7 citations
,
January 2020 in “Skin Pharmacology and Physiology” Standard nail varnish effectively prevents follicular penetration of certain substances.
7 citations
,
July 2018 in “International Journal of Applied Pharmaceutics” Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
5 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
5 citations
,
January 2020 in “Journal of Dermatology and Dermatologic Surgery” Caffeine may benefit skin and hair health but more research is needed to confirm its effectiveness in dermatology.
4 citations
,
February 2022 in “Journal of Pharmaceutical and Biomedical Analysis” The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.
4 citations
,
September 1999 in “Journal of Clinical Forensic Medicine” Caffeine in hair might help identify people, but it's not always reliable.
2 citations
,
January 2022 in “Materials today: proceedings” Caffeine may be good for hair growth and skin care because it binds well with keratin.
1 citations
,
July 2023 in “Cosmetics” The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
1 citations
,
August 2020 in “British Journal of Dermatology” Caffeine may protect hair follicles from stress-related hair loss.
1 citations
,
February 2020 in “PubMed” The topical solution improved hair density and appearance in men with androgenetic alopecia.
January 2026 in “AAPS PharmSciTech” Liposomal formulations with caffeine and cafestol enhance skin penetration effectively.
January 2026 in “British Journal of Dermatology” Caffeine and DMG increase calcium influx in hair follicle cells without being toxic.
October 2025 in “Journal of Drugs in Dermatology” Topical caffeine can help with hair growth and reduce hair loss safely.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
August 2025 in “Journal of Cosmetic Dermatology” The shampoo with DMG-Na and caffeine effectively reduces hair loss and improves hair density in men.
June 2025 in “Current Issues in Molecular Biology” Minoxidil, caffeine, and biotin can improve hair shine by restoring certain genes.
May 2025 in “International Journal of Cosmetic Science” Caffeine and adenosine in shampoo may boost hair growth and change scalp microbes and lipids.
TrichoSol™ effectively stabilizes various hair treatment ingredients for different durations.