September 2014 in “Hair transplant forum international” Caffeine, niacinamide, and panthenol may improve hair growth, fullness, and healing when applied to the scalp.
The optimal concentration for caffeine release in gel form is 0.2% caffeine and 2.3% chitosan.
Nanoparticles with caffeine can be used for slow, continuous hair growth stimulation.
Caffeine therapy helped hair recovery after chemical and traction damage.
May 2025 in “International Journal of Innovative Technologies in Social Science” Caffeine causes sleep problems in many medical students.
Caffeine in Alpecin shampoo may help prolong hair root activity and reduce hair loss.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
The caffeine shampoo for hair loss is stable and suitable for use.
November 2013 in “Journal of Mazandaran University of Medical Sciences” Minoxidil with caffeine works better for hair loss than minoxidil alone.
5 citations
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October 2020 in “Giornale italiano di dermatologia e venereologia” The phyto-caffeine shampoo reduced hair loss and improved hair strength in women with hair thinning.
55 citations
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March 2005 in “Neuropharmacology” A neurosteroid can reduce caffeine-induced anxiety in rats.
94 citations
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May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
67 citations
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November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
61 citations
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January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
47 citations
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August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
29 citations
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December 2011 in “British Journal of Dermatology” A new hair treatment with caffeine and other ingredients makes hair thicker and less likely to break.
25 citations
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July 2017 in “Archives of Dermatological Research” Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
12 citations
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March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
9 citations
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July 2014 in “PubMed” The review doesn't clearly say if biotin, caffeine, melatonin, a marine extract, and zinc are effective for treating hair loss.
7 citations
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February 2018 in “International Journal of Pharmaceutics” Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
6 citations
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August 2021 in “International Journal of Cosmetic Science” Using antioxidants on the scalp can make it healthier and decrease hair loss.
6 citations
,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
5 citations
,
January 2025 in “Pharmaceuticals” Coffea arabica shows promise for skin care due to its beneficial compounds.
4 citations
,
July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
3 citations
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April 2019 in “Journal of Dermatological Treatment” Caffeine shows promise for treating some types of hair loss, but more research is needed.
3 citations
,
January 2018 in “International Journal of Cosmetic Science” Hair stiffness increased by 13.2% after caffeine treatment, validating the Stiffness-Angle Law as an effective measurement method.
2 citations
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January 2022 in “Dermatologic Therapy” Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.
2 citations
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August 2020 in “Chemical and Pharmaceutical Bulletin” Rubbing increases drug absorption through hair follicles.
2 citations
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January 2016 Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.