25 citations
,
March 2019 in “Dermatologic therapy” Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.
26 citations
,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
80 citations
,
April 2011 in “Plant physiology” White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
56 citations
,
November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
7 citations
,
August 2013 in “Experimental and Therapeutic Medicine” 1,25-dihydroxyvitamin D3 helps melanocyte precursors from hair follicles grow and produce melanin, aiding vitiligo treatment understanding.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
232 citations
,
June 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling helps heal injuries and could lead to new treatments.
82 citations
,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
17 citations
,
December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
December 2023 in “Journal of Thoracic Disease” Increased EGFR gene variations may predict chemotherapy outcomes in small cell lung cancer patients.
6 citations
,
January 2019 in “Biochemical and Biophysical Research Communications” Sox13 is a useful marker for early hair follicle development but not essential for hair growth.
3 citations
,
May 2025 in “Stem Cell Research & Therapy” Stem cell therapy from umbilical cords may help treat atopic dermatitis.
2 citations
,
March 2023 in “Frontiers in Medicine” Proper cleansing can resolve dermatosis neglecta, which may indicate underlying psychiatric issues.
January 2012 in “Infoscience (Ecole Polytechnique Fédérale de Lausanne)” Human thymus has stem cells that can self-renew and maintain their identity.
101 citations
,
October 2007 in “Journal of Biological Chemistry” Reduced matriptase activity causes skin and hair issues in both humans and mice.
28 citations
,
June 2012 in “International Journal of Molecular Medicine” Radiation damages hair stem cells and changes keratin expression, with Krt5 as a potential marker for radiation effects.
17 citations
,
October 2023 in “Molecules” Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.
11 citations
,
January 2021 in “British Journal of Dermatology” Mutations in the AP1B1 gene cause a new syndrome with skin, hearing, and developmental issues.
2 citations
,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
2 citations
,
December 1973 in “Calcified tissue research” Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
34 citations
,
August 2012 in “Calcified Tissue International”
24 citations
,
March 2009 in “Journal of the European Academy of Dermatology and Venereology” Scalp pain is a common symptom in people with active hair loss from telogen effluvium.
391 citations
,
January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
April 2017 in “Our Dermatology Online” Using cosmetics made elderly people feel more comfortable and attractive.
January 1982 in “Journal of The American Academy of Dermatology” Experts discussed treatments for skin conditions in children, emphasizing hydration, cautious medication use, and early intervention for infections.
276 citations
,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
153 citations
,
March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.