January 2026 in “Dermatology Reports” Upadacitinib improved symptoms and hair regrowth in a teen with multiple autoimmune conditions.
January 2025 in “Nanoscale Advances” The nanocomposite effectively targets lung cancer cells without harming normal cells.
July 2024 in “Journal of Controlled Release” Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
21 citations
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September 2008 in “Brain Research” Neurosteroids in the brain can increase or decrease seizure risk in mice.
April 1992 in “Current opinion in therapeutic patents” New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
10 citations
,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
10 citations
,
November 2018 in “Nature Biotechnology” Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
June 2010 in “Journal of Chemical Crystallography” The compound was successfully made and shows potential for treating prostate cancer.
The treatment showed promising results in improving advanced-stage hair loss.
18 citations
,
December 2005 in “Journal of Medicinal Chemistry” A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
8 citations
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June 2017 in “Steroids” New chemical compounds were made that effectively block an enzyme linked to prostate growth.
December 2024 in “Ankara Universitesi Eczacilik Fakultesi Dergisi” Black cumin has many health benefits and potential for new medicines.
29 citations
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January 2020 in “BioMed Research International” Sinapic acid may help fight obesity and promote hair growth.
27 citations
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February 2017 in “Clinical, Cosmetic and Investigational Dermatology” New compounds were found to help increase hair growth and decrease hair loss.
March 2023 in “Journal of Applied Biomedicine” Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.
33 citations
,
January 1997 in “Journal of Investigative Dermatology” May 2024 in “Archives of Dermatological Research” TAT-GILZ peptide promotes hair growth by boosting stem cell activity.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
5 citations
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February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
6 citations
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January 2024 in “ACS Medicinal Chemistry Letters” Cepharanthine and berbamine may affect SK channels, influencing their therapeutic effects.
December 2024 in “Jurnal Ilmiah Farmasi (Scientific Journal of Pharmacy)” Nanotechnology could improve lavender oil's effectiveness, but more research is needed.
Nanocarriers improve acne treatment by enhancing drug delivery and reducing side effects.
43 citations
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May 1999 in “Journal of Biological Chemistry” Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
December 2023 in “Natural product research” Lignans from Urtica triangularis may help treat benign prostatic hyperplasia (BPH).
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
21 citations
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March 2002 in “Neurology” Dopamine agonists like pramipexole and ropinirole can cause reversible hair loss.
143 citations
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May 2002 in “PubMed” LGD1069 effectively prevents breast tumors in mice without toxicity.
May 2026 in “Advanced Pharmaceutical Bulletin” This study investigated the use of black cumin oil-based nanostructured lipid carriers (NLCs) to enhance the therapeutic effect of fluticasone propionate (FP) for psoriasis treatment. The optimized NLCs, characterized by a size of 171.3 nm and a zeta potential of -32.3 mV, demonstrated superior drug deposition in the skin and permeation compared to a marketed cream. In vivo tests on imiquimod-induced psoriatic mice showed a 77% improvement in the Psoriasis Area and Severity Index (PASI) score, along with significant reductions in IL-6 and IL-1α levels, indicating decreased inflammation. The study concluded that the black cumin oil-based NLC formulation provides better skin targeting, penetration, and anti-inflammatory effects than standard treatments.
1 citations
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February 2023 in “Ibrain” Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
11 citations
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March 2017 in “Journal of Biomedical Semantics” The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.